You Searched For: ENZO LIFE SCIENCES

Catalog Number: (ENZOALX270013M001)

Supplier: ENZO LIFE SCIENCES

Description: Esterase inhibitor

UOM: 1 * 1 mg

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Catalog Number: (ENZOBMLC1140005)

Supplier: ENZO LIFE SCIENCES

Description: Nicotinic acetylcholine receptor ligand.

UOM: 1 * 5 mg

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Catalog Number: (ENZOBMLPI1550005)

Supplier: ENZO LIFE SCIENCES

Description: Specific non-chelating small-molecule inhibitor of MMP-12 (IC50 = 14 nM). At higher concentrations it inhibits other MMPs, but spares MMP-1, making it a valuable tool for investigation of MMP activity and function.

UOM: 1 * 5 mg

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Supplier: ENZO LIFE SCIENCES

Description: JAK inhibitor

Catalog Number: (ENZOADISAB4100100)

Supplier: ENZO LIFE SCIENCES

Description: FLAG-tag stands for an octapeptide with a sequence of DYKDDDDK. It is a polypeptide protein tag that can be added to a protein using recombinant DNA technology. It is widely used for affinity chromatography to purify recombinant proteins from variety of systems. It can also be used in the isolation of protein complexes with multiple subunits. A FLAG-tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a FLAG-tag to this protein allows one to follow the protein with an antibody against the FLAG sequence, such as in ELISA, Western Blot, etc.

UOM: 1 * 100 µG

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Supplier: ENZO LIFE SCIENCES

Description: ERp57 (also known as Grp58), a member of the Thioredoxin superfamily, is an ER protein with disulfide isomerase activity. It has been shown to increase after oncogenic transformation and to be a component of the MHC Class I peptide-loading complex.

Catalog Number: (ENZOBMLKI1030001)

Supplier: ENZO LIFE SCIENCES

Description: Protease inhibitor cocktail

UOM: 1 * 1 SET

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Catalog Number: (ENZOADISRA1000D)

Supplier: ENZO LIFE SCIENCES

Description: The Estrogen receptors (ER), mainly ERalpha and ERbeta, are members of the nuclear steroid hormone receptor family and are composed of three domains, an N-terminal domain required for maximal transactivation function (TAF), a DNA binding domain, and a steroid binding domain. Estrogen has pleiotropic effects on the growth, development, and maintenance of diverse tissues.

UOM: 1 * 50 µG

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Catalog Number: (ENZOBMLP1060001)

Supplier: ENZO LIFE SCIENCES

Description: PKA substrate

UOM: 1 * 1 mg

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Catalog Number: (ENZOALX850025KI01)

Supplier: ENZO LIFE SCIENCES

Description: This kit offers a set of seven different MAbs specific for tyrosine phosphorylation sites. Phosphorylation patterns in a given cell extract may differ when probed with different antibodies due to sequence specificity. Recognition therefore depends on two criteria: Phosphorylation and surrounding aa motif. If one of the two criteria is not fulfilled, the antibody will not detect the phosphorylation site. Specificity has been determined by epitope mapping using degenerated phosphopeptide libraries.

UOM: 1 * 1 SET

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Catalog Number: (ENZOENZ42731)

Supplier: ENZO LIFE SCIENCES

Description: The procedure for labeling of DNA probes with a polynucleotide 'tail' containing hapten-labeled nucleotides was developed by Enzo. In such terminal labeling reactions, terminal transferase catalyzes the addition of nucleotides to any 3'-OH terminus in a template independent manner. This rapid and convenient nonradioactive labeling procedure is free of any sequence bias that is normally observed in random priming or nick translation reactions. Terminal labeling is an ideal procedure for the labeling of oligonucleotides.

UOM: 1 * 1 KIT

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Catalog Number: (ENZOALX5224400050)

Supplier: ENZO LIFE SCIENCES

Description: Collagen is the main component in connective tissue and helps to provide support for tissues. It is made up of several classes, with Type 1 collagen being the most common.

UOM: 1 * 50 mL

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Catalog Number: (ENZOENZ51008100)

Supplier: ENZO LIFE SCIENCES

Description: GFP-Certified™ Nuclear-ID™ Red Cell Cycle Analysis Kit provides a convenient approach for studying the induction and inhibition of cell cycle progression by flow cytometry.

UOM: 1 * 1 KIT

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Catalog Number: (ENZOADI905762100)

Supplier: ENZO LIFE SCIENCES

Description: Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serine binds to the GSK-3β priming phosphate position and prevents binding of alternative substrates. In addition to insulin signaling, GSK-3β participates in the Wnt signaling pathway, where it forms a complex with axin, beta-catenin and adenomatous polyposis coli (APC) protein. In the presence of Wnts, GSK-3β is unable to phosphorylate beta-catenin, which leads to stabilization of beta-catenin. The Wnt pathway inactivates GSK-3β via the proteins, Dishevelled and FRAT, which disrupt the interaction of GSK-3β with axin, beta-catenin, and APC. Clinically, there is considerable interest in GSK-3β inhibitors because they may mimic the effect of insulin or reduce the hyperphosphorylation of Tau that is observed in Alzheimer's Disease.

UOM: 1 * 100 µG

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Supplier: ENZO LIFE SCIENCES

Description: Calcium dye

Catalog Number: (ENZOADIKAMCC006E)

Supplier: ENZO LIFE SCIENCES

Description: Centromere protein A (CENP-A), a 17-19 kDa centromere-specific histone variant, is 62% identical to the carboxy-terminal domain of histone H3.  In the presence of DNA, CENP-A forms an octameric complex with histones H4, H2A, and H2B.  CENP-A defines active centromere regions by forming centromere-specific nucleosomes on which kinetochores are assembled.  CENP-A resides specifically in the inner plate of the kinetochore, and is essential for kinetochore targeting of CENP-C and other kinetochore components.  CENP-A is required for nucleosomal packaging of centromeric DNA at interphase.

UOM: 1 * 100 µG

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