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Anti-HSP90B1 Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: Anti-HSP90B1 Rabbit Polyclonal Antibody

Image Unavailable-ENZOADISPA829D

Anti-HSP60 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.

Product Image-ENZOADISPA827F

Anti-KDEL Mouse Monoclonal Antibody [clone: 10C3]

Supplier: ENZO LIFE SCIENCES
Description: Anti-KDEL Mouse Monoclonal Antibody [clone: 10C3]

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Anti-HSP90 Mouse Monoclonal Antibody (DyLight® 488)

Supplier: ENZO LIFE SCIENCES
Description: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

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Anti-HSF2 Rat Monoclonal Antibody

Catalog Number: (ENZOADISPA960E)
Supplier: ENZO LIFE SCIENCES
Description: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.
UOM: 1 * 100 µG
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Human recombinant alpha-A-Crystallin,HIS tag

Supplier: ENZO LIFE SCIENCES
Description: Produced in<i> E. coli</i>. Human αA-Crystallin is fused at the N-terminus to a His-tag.

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Human recombinant HSP40/Hdj1 (from E. coli)

Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.

Product Image-ENZOADISPA895D

Anti-HMOX1 Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin.

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Recombinant thioredoxin (from E. coli), HIS tag

Catalog Number: (ENZOADISPP8921)
Supplier: ENZO LIFE SCIENCES
Description: Thioredoxin (Trx) is a redox protein of approximately 12 kDa. Its primary domain is conserved across a number of Trx family members and contains a conserved catalytic site Cys-Gly-Pro-Cys. It is ubiquitous and found in many organisms from bacteria to mammals. Trx has been shown to function in cell proliferation, redox signaling and inhibition of apoptosis.
UOM: 1 * 1 mg
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Anti-KDEL Receptor Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: The tetrapeptide KDEL, located at the carboxy-terminal sequences of luminal proteins, is a retrieval motif essential for the precise sorting of these proteins along the secretory pathway. KDEL proteins perform essential functions in the endoplasmic reticulum (ER) related to protein folding as well as assembly. The localization of chaperones and other soluble proteins to the ER is achieved by their continuous retrieval from post-ER compartments by the KDEL receptor (Erd2p), which is a membrane protein localized in the Golgi apparatus.

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Human recombinant Calnexin (lumenal domain) (from E. coli)

Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.

Image Unavailable-ENZOADISPP892200

Recombinant thioredoxin (from E. coli), HIS tag

Catalog Number: (ENZOADISPP892200)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>. <i>E. coli</i> thioredoxin is fused at the N-terminus to a His-tag.
UOM: 1 * 200 µG
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Cyclosporin C

Catalog Number: (ENZOALX380282M005)
Supplier: ENZO LIFE SCIENCES
Description: Immunosuppressant
UOM: 1 * 5 mg
Image Unavailable-ENZOALX385025M005

8-Isopentenylnaringenin ≥98% (by 1H-NMR)

Catalog Number: (ENZOALX385025M005)
Supplier: ENZO LIFE SCIENCES
Description: Prenyl flavonoid. Phytoestrogen. Selective, non-steroidal estrogen receptor α (ERα) ligand. Potent inhibitor of angiogenesis in vitro and in vivo. Chemopreventive agent against cancer induced by heterocyclic amines.
UOM: 1 * 5 mg
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Demecolcine ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Demecolcine ≥98% (by HPLC)

Image Unavailable-ENZOALX430025M005

(-)-p-Bromotetramisole oxalate ≥98% (by HPLC)

Catalog Number: (ENZOALX430025M005)
Supplier: ENZO LIFE SCIENCES
Description: Potent alkaline phosphatase inhibitor. Mimics the action of orthovanadate in the potentiation of fluorouracil antiproliferative activity. Cell permeable. 
UOM: 1 * 5 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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