4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 2-(4-Hydroxybenzylidene)malononitrile, Tyrphostin 8, α-Cyano-(4-hydroxy)cinnamonitrile

BMLPR1130010 BMLPR1130050
ENZOBMLPR1130010EA 101 GBP
ENZOBMLPR1130010 ENZOBMLPR1130050
4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)
4-Hydroxybenzylidenemalononitrile

The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).


  • Calcineurin inhibitor


Light orange solid.


Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml).

Formula: C₁₀H₆N₂O
MW: 170,2 g/mol
Storage Temperature: Ambient
MDL Number: MFCD00020189
CAS Number: 3785-90-8
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