You Searched For: Protamine+sulphate

Supplier: MP Biomedicals

Description: Storage: Room Temperature, desiccate
Protamine sulfate is a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish, which has the property of neutralizing heparin. Because of having many basic amino acids (mostly arginine) protamine contains far greater nitrogen than other proteins. Its molecular weight is relatively small. Histone and other basic proteins in the testes of unmatured fishes convert into protamine along with the growth of the fishes. In the testes, protamine takes the form of nucleoprotamine linked with DNA.
Protamine Sulfate is a raw material for study preparations like insulin compounds, and etc. It is used in separation and refining of vaccines. It is a reagent for removing nucleic acids from enzyme solution for the purpose of easy separation and refining. Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Inhibits lipoprotein lipase. Protamine sulfate shown to inhibit the classical pathway of complement. It inhibits turnover of lipoproteins by lipoprotein lipase.

Supplier: MP Biomedicals

Description: Protamine sulphate is a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish, which has the property of neutralizing heparin. Because of having much basic amino acids (mostly arginine) protamine contains far greater nitrogen than other proteins. Its molecular weight is relatively small. Histone and other basic proteins in the testes of unmatured fishes convert into protamine along with the growth of the fishes. In the testes protamine takes the form of nucleoprotamine linked with DNA.

Catalog Number: (BOSSBS-6447R-HRP)

Supplier: Bioss

Description: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Protamines are cross-linked by interchain disulfide bonds around the DNA-helix. Protamines are localised in the nucleus. This protein is found only in the testis and belongs to the protamine P1 family.

UOM: 1 * 100 µl

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Catalog Number: (1578612.)

Supplier: USP

Description: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

UOM: 1 * 2,85 mg

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Catalog Number: (USBI131834)

Supplier: US Biological

Description: Anti-PRM1 Mouse Polyclonal Antibody

UOM: 1 * 50 µG

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Catalog Number: (BOSSBS-12280R)

Supplier: Bioss

Description: Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis (By similarity).

UOM: 1 * 100 µl

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Catalog Number: (PRSI91-653)

Supplier: ProSci Inc.

Description: Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.

UOM: 1 * 50 µG

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Catalog Number: (ABCAAB66978-50)

Supplier: Abcam

Description: Anti-HSP1 / Protamine P1 Mouse Polyclonal Antibody

UOM: 1 * 50 µG

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Catalog Number: (ANTIA313708-96)

Supplier: ANTIBODIES.COM

Description: Human Protamine 2 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Protamine 2 in serum, plasma, and other biological fluids.

UOM: 1 * 96 Tests

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Catalog Number: (ANTIA78670-96)

Supplier: ANTIBODIES.COM

Description: Human HSP1/Protamine P1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human HSP1/Protamine P1 in serum, plasma, tissue homogenates, and other biological fluids.

UOM: 1 * 96 Tests

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Catalog Number: (PRSI30-898)

Supplier: ProSci Inc.

Description: TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines.Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).

UOM: 1 * 50 µG

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Catalog Number: (PRSI30-429)

Supplier: ProSci Inc.

Description: CDY1 containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein.This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

UOM: 1 * 100 µG

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Supplier: Merck

Description: Ammonium sulphate, Millipore®

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Supplier: Merck

Description: Tetrahexylammonium hydrogen sulphate, Supelco®

Catalog Number: (31014-100G)

Supplier: Merck

Description: Mercury(II) sulphate, Supelco®

UOM: 1 * 100 g

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Catalog Number: (8.41034.0050)

Supplier: Merck

Description: Aminoacetonitrile sulphate for synthesis, Sigma-Aldrich®

UOM: 1 * 50 g

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