You Searched For: N,N-Dimethylsphingosine,+D-erythro

Supplier: ENZO LIFE SCIENCES AG

Description: Sphingosine kinase inhibitor

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Catalog Number: (BOSSBS-2652R-A750)

Supplier: Bioss

Description: Catalyses the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-2652R-A680)

Supplier: Bioss

Description: Catalyses the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.

UOM: 1 * 100 µl

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Catalog Number: (8.18289.0001)

Supplier: Merck

Description: (+)-Ethyl-4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside for synthesis

UOM: 1 * 1 g

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Catalog Number: (ENZOBMLSL2220025)

Supplier: ENZO LIFE SCIENCES AG

Description: Negative control for D-<i>erythro</i>-MAPP

UOM: 1 * 25 mg

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Supplier: ENZO LIFE SCIENCES AG

Description: Alkaline ceramidase inhibitor

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Supplier: Apollo Scientific

Description: N-BOC-erythro-L-β-Methylphenylalanine 97%

Supplier: ENZO LIFE SCIENCES AG

Description: Sphingosine precursor

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Supplier: Cayman Chemical

Description: D-erythro-Sphingosine C-17 is a naturally-occurring but uncommon form of sphingosine, accounting for approximately 13% of the sphingosine in human skin.

Catalog Number: (ENZOBMLSL1430001)

Supplier: ENZO LIFE SCIENCES AG

Description: S1P receptor ligand.

UOM: 1 * 1 mg

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Supplier: Thermo Scientific

Description: Appearance: White to cream Powder or waxy solid

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Catalog Number: (ENZOALX306017C500)

Supplier: ENZO LIFE SCIENCES AG

Description: D-erythro-Sphingosine-1-phosphate (caged) ≥95%

UOM: 1 * 500 µG

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Supplier: ENZO LIFE SCIENCES AG

Description: Ceramide-activated protein kinase activator.

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Catalog Number: (ENZOBMLEI1550100)

Supplier: ENZO LIFE SCIENCES AG

Description: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.

UOM: 1 * 100 mg

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Catalog Number: (H52099.03)

Supplier: Thermo Scientific

Description: erythro-N-Boc-3,5-difluoro-L-phenylalanine epoxide 95%

UOM: 1 * 1 g

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Supplier: ENZO LIFE SCIENCES AG

Description: A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

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