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Catalog Number: (PRSI57-455)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50

UOM: 1 * 400 µl

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Catalog Number: (PRSI62-415)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.

UOM: 1 * 400 µl

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Catalog Number: (PRSI62-402)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.

UOM: 1 * 400 µl

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Catalog Number: (PRSI57-460)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000

UOM: 1 * 400 µl

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Catalog Number: (PRSI33-188)

Supplier: ProSci Inc.

Description: This antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone. This progesterone receptor antibody is excellent for immunohistochemical staining of formalin/paraffin tissues.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-210)

Supplier: ProSci Inc.

Description: Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300 kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin antibody negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Thyroglobulin antibody, combined with calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin antibody, combined with TTF1 antibody, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-177)

Supplier: ProSci Inc.

Description: Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Myogenin antibody labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms’ tumor.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-178)

Supplier: ProSci Inc.

Description: This antibody reacts with an extracellular domain (close to transmembrane) of NCAM (Neural cell adhesion molecule), also called CD56. Three isoforms of NCAM/CD56 are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. NCAM antibody recognises two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). NCAM antibody plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-216)

Supplier: ProSci Inc.

Description: This antibody is specific for a 17-26 kDa protein, which is identified as the cytokine TNF alpha (Tumor Necrosis Factor alpha). It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. It is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. It exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-179)

Supplier: ProSci Inc.

Description: Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). The fourth neurofilament subunit is alpha internexin in the central nervous system and peripherin in the peripheral nervous system.

UOM: 1 * 100 µG

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Catalog Number: (PRSI16-999)

Supplier: ProSci Inc.

Description: Anti-LPCAT3 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI18-005)

Supplier: ProSci Inc.

Description: Anti-DPYSL4 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI18-029)

Supplier: ProSci Inc.

Description: Anti-CLCC1 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI18-019)

Supplier: ProSci Inc.

Description: Anti-HSPA4L Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI18-028)

Supplier: ProSci Inc.

Description: Anti-SPG20 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI18-004)

Supplier: ProSci Inc.

Description: Anti-SLU7 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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