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Cefoperazone sodium salt ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including β-lactamase strains (3 – 4 µg/ml inhibits 90% of S. <i>aureus</i> growth). It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.

MSDS

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β-D-Glucose ≥98%, crystalline solid

Supplier: Cayman Chemical
Description: β-D-Glucose ≥98%, crystalline solid

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Taurodeoxycholic acid sodium salt ≥95%

Supplier: Cayman Chemical
Description: Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid. Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally. Serum levels of taurodeoxycholic acid increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans.

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6-OAU ≥98%

Supplier: Cayman Chemical
Description: GPR84 is a Gαi protein-coupled receptor that is activated by medium-chain free fatty acids, but only at micromolar concentrations. GPR84 is expressed in leukocytes and its expression is further induced by LPS.

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WYE-125132 ≥98%, crystalline solid

Supplier: Cayman Chemical
Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC<sub>50</sub> = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.

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Anti-GPR41 Rabbit Polyclonal Antibody

Catalog Number: (CAYM16104-1)
Supplier: Cayman Chemical
Description: Anti-GPR41 Rabbit Polyclonal Antibody
UOM: 1 * 1 items
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Coenzyme A sodium salt hydrate ≥95%

Supplier: Cayman Chemical
Description: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

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MitoPQ ≥98%

Supplier: Cayman Chemical
Description: MitoPQ is comprised of a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat. Driven by membrane potential, it accumulates selectively in the mitochondrial matrix where it produces superoxide by redox cycling at the flavin site of complex I. Thus, MitoPQ selectively increases superoxide production within mitochondria and can be used as a tool either in cells or in vivo to investigate the role of mitochondrial superoxide in pathology and redox signaling.

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1-Methoxy-5-methylphenazinium methyl sulphate ≥98%, crystalline solid

Supplier: Cayman Chemical
Description: 1-Methoxy-5-methylphenazinium (methyl sulphate) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes. It can be used to visualise NAD-linked dehydrogenase activities.

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Menaquinone 7 ≥98%

Supplier: Cayman Chemical
Description: Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 µM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 µg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.

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3,6-Bis(4-(bis(2-hydroxydodecyl)amino)butyl)piperazine-2,5-dione ≥95%

Catalog Number: (CAYM36700-25)
Supplier: Cayman Chemical
Description: 3,6-Bis(4-(bis(2-hydroxydodecyl)amino)butyl)piperazine-2,5-dione ≥95%
UOM: 1 * 25 mg

New Product


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Gestrinone ≥98%, crystalline solid

Supplier: Cayman Chemical
Description: Gestrinone is a synthetic steroid used occasionally to treat endometriosis.

Product Image-CAYM25922-100

Anti-STING mouse monoclonal antibody [clone: 8E7]

Catalog Number: (CAYM25922-100)
Supplier: Cayman Chemical
Description: Anti-STING mouse monoclonal antibody [clone: 8E7]
UOM: 1 * 100 µG
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Phloretin

Supplier: Cayman Chemical
Description: Phloretin

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Long-Chain Cis/Trans Isomer Fatty Acid Methyl Ester Mixture

Catalog Number: (CAYM29363-5)
Supplier: Cayman Chemical
Description: Long-chain cis/trans isomer fatty acid methyl ester mixture contains cis and trans isomers of several fatty acids. It is intended for use as a reference standard for the detection of long-chain fatty acids in various sample types by GC-MS.
UOM: 1 * 5 mL

New Product


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NF-κB Activation Inhibitor III ≥99%

Supplier: Cayman Chemical
Description: NF-κB Activation Inhibitor III ≥99%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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