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Catalog Number: (ENZOBMLKI1110020)
Supplier: ENZO LIFE SCIENCES
Description: 50 mM HEPES, pH 7,4, 100 mM NaCl, 0,1% CHAPS, 10 mM DTT, 1 mM EDTA, 10% glycerol.
UOM: 1 * 20 mL


Catalog Number: (ENZOBMLKC1250500)
Supplier: ENZO LIFE SCIENCES
Description: K⁺ channel activator.
UOM: 1 * 500 mg


Catalog Number: (ENZOBMLKI1040050)
Supplier: ENZO LIFE SCIENCES
Description: Fluor de Lys® Substrate is a highly sensitive and convenient alternative to radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. The Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.). Deacetylation of the substrate sensitizes the substrate so that, in a second step, treatment with the Fluor de Lys® Developer produces a fluorophore. Histone deacetylases from all known classes have been successfully assayed with the Fluor de Lys® Substrate. These include human HDACs 1, 2, 3 and 8 (class I), human HDACs 4 and 9 (class II) and the sirtuins yeast Sir2, human SIRT1 and human SIRT2 (class III; reaction must include the sirtuin substrate NAD+). The substrate is cell-permeable and serves as the basis for the HDAC Cellular Activity Assay Kit (Prod. No. BML-AK503). NOTE: Must be used in conjunction with Fluor de Lys® Developer (Prod. No. BML-KI105). Sufficient for 100-1000 assays of HDACs or sirtuins (50 µl reaction volume, 50-500 µM (substrate).
UOM: 1 * 50 µl


Catalog Number: (ENZOBMLKI1360001)
Supplier: ENZO LIFE SCIENCES
Description: EGTA buffer, 2X
UOM: 1 * 1 mL


Catalog Number: (ENZOBMLJ1310005)
Supplier: ENZO LIFE SCIENCES
Description: Metabolite of triazolam.
UOM: 1 * 5 mg


Catalog Number: (ENZOBMLKI1310020)
Supplier: ENZO LIFE SCIENCES
Description: PTP1B 2x assay buffer
UOM: 1 * 20 mL


Supplier: ENZO LIFE SCIENCES
Description: Major metabolite of zolpidem.

Supplier: ENZO LIFE SCIENCES
Description: K⁺ channel blocker.

Supplier: ENZO LIFE SCIENCES
Description: K⁺ channel activator.

Catalog Number: (ENZOBMLKI1070001)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic chromophore. Ex(max): 380nm, Em(max): 460nm. Reference compound.
UOM: 1 * 1 mL


Catalog Number: (ENZOBMLKI1761250)
Supplier: ENZO LIFE SCIENCES
Description: FLUOR DE LYS® Developer II is an essential reagent for signal generation in assays done with the FLUOR DE LYS®-HDAC8, FLUOR DE LYS®-SIRT1 and FLUOR DE LYS®-SIRT2 substrates. Deacetylation of the FLUOR DE LYS® substrate sensitises it so that, in a second step, treatment with the FLUOR DE LYS® Developer II produces a fluorophore. Typically, an ‘inhibitor stop’ will be included in the 1X Developer dilution (e.g. nicotinamide for sirtuins).
UOM: 1 * 1,25 mL


Catalog Number: (ENZOBMLKI1900002)
Supplier: ENZO LIFE SCIENCES
Description: 3', 5'-cGMP substrate
UOM: 1 * 2 mL


Catalog Number: (ENZOBMLP1520001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide sequence, RRApTVA, has been found to be an excellent substrate for both PP2A and PP2C phosphatases.
UOM: 1 * 1 mg


Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate cleaved by plasma kallikrein and kallikrein 8, but not plasmin; by papain; and by most cathepsins (cathepsins B, C/DPP-I, F, K/O2, L, L2/V, O, S, and X/Z). Ex.: 380 nm, Em.: 460 nm, although the following Ex/Em can also be used: 355,375/440,450.

Catalog Number: (ENZOBMLP1450001)
Supplier: ENZO LIFE SCIENCES
Description: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP1490001)
Supplier: ENZO LIFE SCIENCES
Description: Akt substrate
UOM: 1 * 1 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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