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Image Unavailable-AATB2087

5.1WS succinimidyl ester [TQ5.1WS SE], Tide Quencher™

Catalog Number: (AATB2087)
Supplier: AAT BIOQUEST
Description: Tide Quencher™ 5.1WS (TQ5.1WS) is a non-fluorescent molecule designed to efficiently quench the fluorescence of common NIR fluorophores such as Cy5, Cy5.5, Alexa Fluor® 647, Alexa Fluor® 647, iFluor® 647 and iFluor® 680.
UOM: 1 * 1 mg

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Product Image-AATB5208

FMOC-Asp(TQ3)-OH for biomolecular labeling

Catalog Number: (AATB5208)
Supplier: AAT BIOQUEST
Description: FMOC-Asp(TQ3)-OH is a building block for in-sequence Lys labeling by Tide Quencher™ 3 (TQ3).
UOM: 1 * 100 mg
Product Image-AATB5206

FMOC-Asp(TQ2)-OH for biomolecular labeling

Catalog Number: (AATB5206)
Supplier: AAT BIOQUEST
Description: FMOC-Asp(TQ2)-OH is a building block for in-sequence Lys labeling by Tide Quencher™ 2 (TQ2).
UOM: 1 * 100 mg
Product Image-AATB5256

FMOC-Lys(TQ2)-OH for biomolecular labeling

Catalog Number: (AATB5256)
Supplier: AAT BIOQUEST
Description: FMOC-Lys(TQ2)-OH is a building block for in-sequence Lys labeling by Tide Quencher™ 2 (TQ2).
UOM: 1 * 100 mg
Product Image-AATB13541

Covipyte™ TF670 Peptide Substrate

Supplier: AAT BIOQUEST
Description: Covidyte™ TF670 is a peptide substrate containing 14 amino acid sequence (KTSAVLQSGFRKME) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and Tide Fluor™ 5 (TF5) as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of TF5 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolysed by coronavirus proteases, the TF5 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of TF5. Covidyte™ TF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. TQ5-TF5 pair has been proven to an extremely effective FRET pair for developing FRET protease substrates. Comparing to the commonly used EDANS substrates (such as Covidyte™ EN450), the TF670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Product Image-AATB2240

Tide Fluor™ 1 CPG 500 Å, Tide Fluor™ fluorescent probe

Catalog Number: (AATB2240)
Supplier: AAT BIOQUEST
Description: TF1 is designed to be a superior fluorophore alternative to EDANS.
UOM: 1 * 100 mg
Product Image-AATB13543

Covipyte™ IF670

Supplier: AAT BIOQUEST
Description: Covidyte™ IF670 is a peptide substrate containing 12 amino acid sequence (VNSTLQSGLRKM) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and iFluor® 670 as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of iFluor® 670 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolyzed by coronavirus proteases, the iFluor® 670 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of iFluor® 670. Covidyte™ IF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. Comparing to the commonly used EDANS substrates (such as Covidyte™ ED450), the iFluor® 670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Product Image-AATB6008

3'-DABCYL CPG 1000 Å for oligonucleotide labeling

Catalog Number: (AATB6008)
Supplier: AAT BIOQUEST
Description: DABCYL is one of the most commonly used dark quenchers for labeling oligos and peptides.
UOM: 1 * 1 g
Image Unavailable-ENZOENZCHM1650001

EQ1 NHS ester amine-reactive quencher dye

Catalog Number: (ENZOENZCHM1650001)
Supplier: ENZO LIFE SCIENCES
Description: Amine-reactive quencher dye has a broad visible absorption but no detectable fluorescence emission in fluorescence resonance energy transfer (FRET) applications.
UOM: 1 * 1 mg
Image Unavailable-432199-500MG

Leucoberbelin Blue I 65% (dye content), Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Leucoberbelin blue I has been used as a quencher in time-resolved fluorescence QRET technique for receptor-ligand interaction screening and to detect oxidized manganese species in Mn(II) (manganese) oxidation assays.

Image Unavailable-ENZOENZCHM2080001

EQ0 NHS ester amine-reactive quencher dye

Catalog Number: (ENZOENZCHM2080001)
Supplier: ENZO LIFE SCIENCES
Description: Amine-reactive quencher dye has a broad visible absorption but no detectable fluorescence emission in fluorescence resonance energy transfer (FRET) applications.
UOM: 1 * 1 mg
Image Unavailable-80501.

Reactive quencher dyes

Supplier: Biotium
Description: Reactive quenchers that act as acceptors in fluorescence resonance energy transfer (FRET) applications.

Image Unavailable-80012.

p-Xylene-bis(N-pyridinium bromide) (DPX)

Catalog Number: (80012.)
Supplier: Biotium
Description: DPX is a positively charged quencher that is often used with ANTS (90010) to study membrane fusion or permeability.
UOM: 1 * 500 mg
Image Unavailable-23007.

Lipofuscin autofluorescence quencher, TrueBlack™

Catalog Number: (23007.)
Supplier: Biotium
Description: TrueBlack™ is a reagent for quenching lipofuscin autofluorescence in tissue sections for immunofluorescence staining. Lipofuscin consists of highly autofluorescent granules of oxidized proteins and lipids that build up in the lysosomes of aging cells. Lipofuscin granules fluoresce brightly in all channels used for fluorescence microscopy and accumulate in a cell and tissue types with age.
UOM: 1 * 1 mL

MSDS


Product Image-70037.

Fluorescent nerve terminal probes and stains

Catalog Number: (70037.)
Supplier: Biotium
Description: Nerve terminal probes are a series of fluorescent cationic styryl dyes developed to follow synaptic activity. These dyes have a lipophilic tail at one end and a hydrophilic cationically charged head group at the other end. The dyes vary in the number of carbons in the lipophilic tail (m) and the number of double bonds linking the two aromatic rings in the dye (n). AM dyes are similar to FM dyes, but contain an additional formaldehyde-fixable amino group in the cationic head.
UOM: 1 * 100 mg
Image Unavailable-ENZOBMLP2280100

TACE substrate II

Catalog Number: (ENZOBMLP2280100)
Supplier: ENZO LIFE SCIENCES
Description: Sensitive fluorogenic substrate for TACE (TNFalpha converting enzyme, ADAM17). Also cleaved by ADAM10 and likely other ADAMs and MMPs. The kcat/Km of TACE for this substrate is 7-fold higher than for the same peptide with the Mca-Dpa fluorophore-quencher pair. FAM fluorescence is quenched by the TAMRA group until cleavage separates them. Ex.: 485 nm, Em.: 535 nm, although the following Ex/Em can also be used: 490,494/515,520 nm. This substrate is useful for inhibitor screening, kinetic analysis, and cellular activity assay.
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
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