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Product Image-EDVOS-48

Ready-to-Load™ Kits, what is PCR and how does it work?

Catalog Number: (EDVOS-48)
Supplier: EDVOTEK
Description: This simulation experiment demonstrates the process of DNA amplification by PCR and how the amplified product is detected by separating the reaction mixture by agarose gel electrophoresis.
UOM: 1 * 1 KIT
Product Image-EDVO371

Experimentation kits, DNA fingerprinting - using PCR

Catalog Number: (EDVO371)
Supplier: EDVOTEK
Description: Students can solve a crime using PCR. Plasmid DNA is provided that, when amplified by PCR, provides products that represent individual DNA profiles.
UOM: 1 * 1 KIT

MSDS


Image Unavailable-BOSSBS-6175R-A680

Anti-RAB5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-6175R-A680)
Supplier: Bioss
Description: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localise to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localisation. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
UOM: 1 * 100 µl
Product Image-BE-409

Experimentation kits, conservation of genetic information

Catalog Number: (BE-409)
Supplier: G-Biosciences
Description: In this lab activity, students learn to perform carefully controlled experiments to generate protein fragments using a proteolysis enzyme and then analyse the protein fragments by electrophoresis. By analysis of protein fragmentation patterns, i.e. protein fingerprints, students learn about protein sequence, structure, and their conservation. Students resolve a set of three functionally identical protein samples selected from throughout the animal kingdom; including human, bovine and sheep. After generating fingerprints by electrophoresis, students examine the protein fingerprint of each sample to determine the degree of conservation.
UOM: 1 * 1 KIT
Image Unavailable-PRSI92-657

S. hygroscopicus recombinant PPT N-acetyltransferase (from E. coli)

Catalog Number: (PRSI92-657)
Supplier: ProSci Inc.
Description: Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant genome can confer resistance to glufosinate herbicide during post-emergent applications.
UOM: 1 * 50 µG
Product Image-EDVO990

Experimentation kits, morphology of cancer cells

Catalog Number: (EDVO990)
Supplier: EDVOTEK
Description: When normal cells are grown in culture they stop growing when they become overcrowded (contact inhibition). Cancer cells in culture grow in an uncontrolled way because they have lost this property. This helps tumours to form in the body. In addition, many different cell types can be present in a single tumour. This experiment allows students to see the differences between normal and cancer cells in both their growth and cell types.
UOM: 1 * 1 items
Product Image-763-0010

Kits: the mystery of the crooked cell, Ready-to-Load™

Catalog Number: (763-0010)
Supplier: EDVOTEK
Description: This simple experiment demonstrates detection of the mutation that causes Sickle Cell Anaemia. In this simulation, students use electrophoresis to separate dyes that represent patient samples and controls.
UOM: 1 * 1 items
Product Image-BE-414

Experimentation kits, size exclusion chromatography

Catalog Number: (BE-414)
Supplier: G-Biosciences
Description: The Size Exclusion Chromatography kit teaches gel filtration or size exclusion chromatography and the use of this method in purification of biological samples. This method is based on separation of protein molecules based on their molecular size. This lab activity involves running size exclusion chromatography for separation of molecules based on their molecular sizes.
UOM: 1 * 1 KIT
Product Image-EDVO112

Kits: analysis of Eco RI cleavage patterns of lambda DNA, Ready-to-Load™

Supplier: EDVOTEK
Description: Ready-to-Load™ kit for introducing the use of restriction enzymes as a tool to digest lambda DNA at specific nucleotide sequences.

Product Image-EDVO103-C

Ready-to-Load™ Kits, PCR

Supplier: EDVOTEK
Description: Ready-to-Load™ PCR kit introduces students to the principles and applications of the Polymerase Chain Reaction (PCR). This simulation experiment does not contain human DNA and does not require a thermal cycler.

Product Image-EDVOS-30

Experimentation kits, how clean is the water we drink and the air we breathe?

Catalog Number: (EDVOS-30)
Supplier: EDVOTEK
Description: With this kit, students sample water and air and then grow any microbes present overnight. A safe and simple way to teach pollution.
UOM: 1 * 1 items
Product Image-763-0007

Kits: why do people look different?, Ready-to-Load™

Catalog Number: (763-0007)
Supplier: EDVOTEK
Description: This kit is for teaching students how people's physical traits are a reflection of their genes. In this simulation, students use electrophoresis to separate dyes which represent genetic traits.
UOM: 1 * 1 KIT
Product Image-EDVO113

Experimentation kits, principles of thin layer chromatography

Catalog Number: (EDVO113)
Supplier: EDVOTEK
Description: This experiment introduces chromatographic theory and methods of thin layer chromatography (TLC). A mixture of dyes are separated on a cellulose-based TLC plate using different solvent systems.
UOM: 1 * 1 items
Product Image-EDVO282

Experimentation kits, principles of enzyme catalysis

Catalog Number: (EDVO282)
Supplier: EDVOTEK
Description: This easy and safe experiment allows students to learn about enzyme catalysis, the nature of enzyme action, and protein structure-function relationship. Students will perform an enzyme assay and determine the rate of the enzymatic reaction.
UOM: 1 * 1 KIT
Product Image-BE-408

Experimentation kits, protein fingerprinting

Catalog Number: (BE-408)
Supplier: G-Biosciences
Description: In this lab activity, students learn to perform simple protein isolation procedures to isolate the protein fingerprint from various fresh tissues. They will compare the protein fingerprints of four different tissues to understand that the function of a particular organ is due to the proteins that are localised to the specific organ. Also included in this kit are four dried protein samples (from mouse liver, brain, heart and lungs) to compare as a control, if fresh tissues cannot be obtained.
UOM: 1 * 1 KIT
Product Image-EDVO115-C

Kits: family pedigree cancer gene detection, Ready-to-Load™

Supplier: EDVOTEK
Description: In this experiment, students determine a pedigree for a family thought to be carriers of a mutation in their p53 genes. This is followed by a diagnostic agarose gel analysis to diagnose the state of the p53 gene in individual family members.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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