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Description: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
Catalog Number: BOSSBS-6175R-A350
UOM: 1 * 100 µl
Supplier: Bioss


Description: Evacuated glass flask containing i.a. electron gun with directly heated tungsten wire cathode and a cylindrical anode. The electron gun emits a divergent electron beam, aimed at an Maltese cross of aluminum placed in the middle of the tube. The cross can be connected electrically. At the same time, light from the filament is also directed towards the cross, so that a comparison can be made between the shadows of different types that appear on the luminescent surface at the far end of the tube. Specifications.
Catalog Number: 765-0089
UOM: 1 * 1 items
Supplier: 3B Scientific


Description: Optical glass components are manufactured with high accuracy polishing and flatness tolerance.
Catalog Number: DIDAPOD010240
UOM: 1 * 1 items
Supplier: DIDALAB


Description: Educational Materials, Optics, Application: Physics, Translucent screen 20×20 cm, attached to a rod with Ø 10 mm
Catalog Number: DIDAPOD010007
UOM: 1 * 1 items
Supplier: DIDALAB


Description: The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2 and NPAS3, which are involved the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed in the adult brain, may be involved in neurogenesis and may control regulatory pathways relevant to psychotic illness and to schizophrenia. It regulates tracheal cell fates in the embryo and is necessary for the development of the posterior spiracles and the salivary gland duct. NPAS3 contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. Efficient DNA binding by NPAS2 requires dimerization with another bHLH protein.
Catalog Number: BOSSBS-11905R
UOM: 1 * 100 µl
Supplier: Bioss


Description: A hands on lab activity to study immunoaffinity chromatography and use a specific antibody to purify antigenic proteins from complex samples. This technique involves performing a chromatography procedure using antigen or antibody immobilised on a chromatographic resin. The solution containing antigen or antibody is passed through the column, which specifically and efficiently captures antibodies (antigen). The captured molecules are eluted from the column as a pure fraction. In this lab activity, students perform immunoaffinity chromatography and learn how this method is utilised in research laboratories.
Catalog Number: BE-507
UOM: 1 * 1 KIT
Supplier: G-Biosciences


Description: Link important STEM concepts using Agarose Gel Electrophoresis.
Catalog Number: EDVOS-46
UOM: 1 * 1 items
Supplier: EDVOTEK


Description: According to Hoffmann, with two city dishes, 0 to 30 ml of grading graded 1/10 ml.
Catalog Number: HECH44286010
UOM: 1 * 1 items
Supplier: GLASWARENFABRIK KARL HECHT


Description: Hands-on simulation of CRISPR-Cas9 to target and treat Cystic Fibrosis.
Catalog Number: EDVO135
UOM: 1 * 1 KIT
Supplier: EDVOTEK


Description: Genetic testing can be used to identify people with a genetic condition which caused them to have an elevated level of cholesterol and which can be fatal. Students can see how genetic testing is carried out and learn about DNA electrophoresis.
Catalog Number: EDVO118-C
UOM: 1 * 1 items
Supplier: EDVOTEK


Description: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
Catalog Number: BOSSBS-6175R-A555
UOM: 1 * 100 µl
Supplier: Bioss


Description: Educational Materials, Optics, Application: Physics, Diode laser, blue, Class II
Catalog Number: DIDAPOD013133
UOM: 1 * 1 items
Supplier: DIDALAB


Description: This comprehensive optical pack allows you to implement and study the basic principles of polarisation of light.
Catalog Number: DIDAPOD060930
UOM: 1 * 1 items
Supplier: DIDALAB


Description: Advanced kit for science education.
Catalog Number: 552-0287
UOM: 1 * 1 items
Supplier: MACHEREY-NAGEL


Description: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
Catalog Number: BOSSBS-6175R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
Catalog Number: BOSSBS-6175R-CY5
UOM: 1 * 100 µl
Supplier: Bioss


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