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Product Image-DIDAPOD060110

High quality prismatic optical bench

Supplier: DIDALAB
Description: Triangular, cast aluminium optical bench

Product Image-216-0428

Pneumatic trough, pp, Nalgene®

Catalog Number: (216-0428)
Supplier: Thermo Fisher Scientific
Description: Replace metal-type troughs with the polypropylene pneumatic trough.
UOM: 1 * 1 items

Environmentally Preferable


Product Image-552-0288

TLC education advanced kit, micro-set F2

Catalog Number: (552-0288)
Supplier: MACHEREY-NAGEL
Description: Advanced kit for science education.
UOM: 1 * 1 KIT
Product Image-EDVO141

Experimentation kits, blood-based cancer diagnostics

Catalog Number: (EDVO141)
Supplier: EDVOTEK
Description: Cancer cells differ from normal cells by the combinations of proteins that are present on their surfaces. Antibodies against these proteins will specifically bind to cancer cells and not to normal cells. This allows early detection of cancer and potentially a way of delivering cancer therapies. In this simulation experiment the reaction of cancer cell markers and their corresponding antigens are demonstrated.
UOM: 1 * 1 items

MSDS


Product Image-DIDAPOD608607

Lens, wide diameter, Magoptic

Supplier: DIDALAB
Description: These wide diameter lenses are used for easy classroom experiments and for aberrations underscoring.

Product Image-EDVOS-49

Kits: in search of my father, Ready-to-Load™

Catalog Number: (EDVOS-49)
Supplier: EDVOTEK
Description: Solve the mystery of two boys separated from their parents a decade ago. Their biological mother is identified by mitochondrial DNA and their biological father from chromosomal DNA.
UOM: 1 * 1 items
Product Image-C111-B

Protein purification columns

Supplier: G-Biosciences
Description: Prepacked purification columns for protein purification. Supplied in packs of five.

Product Image-DIDAPOF010112

Standard prismatic optical bench, DidaFirst

Supplier: DIDALAB
Description: Economical, recent design of prismatic optical bench

Product Image-EDVOS-70

Experimentation kits, how does a doctor test for AIDS?

Catalog Number: (EDVOS-70)
Supplier: EDVOTEK
Description: The body defends itself from attack by infectious agents like bacteria and viruses by producing antibodies. Enzyme linked immunosorbent assays (ELISA) test for antibodies present in the blood, which indicate infection. In this experiment, students perform a simulated ELISA test to identify infected samples and compare them to control samples.
UOM: 1 * 1 items

MSDS


Product Image-EDVO957

Experimentation kits, DNA damage and repair

Catalog Number: (EDVO957)
Supplier: EDVOTEK
Description: According to the World Health Organisation, between two and three million cases of skin cancer occur globally every year. Many of these cases are caused by preventable damage to DNA by UV light. In this experiment, students expose plasmid DNA to shortwave UV light to simulate the effect of sunbathing. The DNA is then analysed by agarose gel electrophoresis to observe the damage.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-0288R-HRP

Anti-TRKB Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0288R-HRP)
Supplier: Bioss
Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0175R-A488

Anti-TRKB Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-0175R-A488)
Supplier: Bioss
Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0175R-CY5.5

Anti-TRKB Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-0175R-CY5.5)
Supplier: Bioss
Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
UOM: 1 * 100 µl
Product Image-BINH1003080

Diffraction/transmission gratings

Supplier: 3B Scientific
Description: Transmission grating for spectroscopic examinations and for experiments on diffraction and interference. Suitable to resolve the sodium D lines.

Product Image-DIDAPOD010007

Screens for optical bench

Supplier: DIDALAB
Description: Educational Materials, Optics, Application: Physics, Translucent screen 20×20 cm, attached to a rod with Ø 10 mm

Product Image-BE-104

DNA fingerprinting kit

Catalog Number: (BE-104)
Supplier: G-Biosciences
Description: This DNA fingerprinting kit allows students to carry out their own criminal investigation by comparing DNA samples collected from suspects to DNA collected at a pseudo-crime scene.
UOM: 1 * 1 KIT
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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