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General purpose gloves, HyFlex® 11-818

Supplier: Ansell
Description: This knitted spandex/nylon liner features a foam nitrile coating on the palm. Under abrasive conditions the ultra-thin FORTIX™ nitrile foam coating lasts up to three times longer than comparable coatings, extending glove life and reducing total cost of ownership.

Product Image-SCTV420060

Universal waste hubs 'Jan'

Supplier: S.C.A.T.
Description: Collect your laboratory waste with our 'Jan' Universal Waste Hub, the smart all-in-one solution for liquid waste. It is a clever combination of lid funnel with tubing and HPLC connections plus an integrated exhaust air filter. Many other innovative details guarantee maximum safety compared to conventional solutions.

Image Unavailable-ENZOALX350404M050

Hydroxytyrosol Acetate

Catalog Number: (ENZOALX350404M050)
Supplier: ENZO LIFE SCIENCES
Description: Hydroxytyrosol acetate is an antioxidant comparable to resveratrol. It is converted to hydroxytyrosol through hydrolysis by esterases.
UOM: 1 * 50 mg
Image Unavailable-CAYM15632-10

7-Ethyl-10-hydroxycamptothecin ≥98%

Supplier: Cayman Chemical
Description: SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC<sub>50</sub> = 8.8 nM) compared to irinotecan (IC<sub>50</sub> >100 nM).

Image Unavailable-BOSSBS-3298R-A488

Anti-NDRG1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-3298R-A488)
Supplier: Bioss
Description: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. May have a growth inhibitory role. Ubiquitous; expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Reduced expression in adenocarcinomas compared to normal tissues. In colon, prostate and placental membranes, the cells that border the lumen show the highest expression.
UOM: 1 * 100 µl
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Anti-Histiocytoma Marker Mouse Monoclonal Antibody (CF405S) [clone: D11]

Supplier: Biotium
Description: In Western blotting, this antibody detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.

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Anti-Histiocytoma Marker Mouse Monoclonal Antibody (CF594) [clone: D11]

Supplier: Biotium
Description: In Western blotting, this antibody detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.

Image Unavailable-BOSSBS-0818R-A680

Anti-MrpL28 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-0818R-A680)
Supplier: Bioss
Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL28 is a 39S subunit protein, a part of which was originally isolated by its ability to recognise tyrosinase in an HLA A24 restricted fashion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2130R-A350

Anti-MKI67 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-2130R-A350)
Supplier: Bioss
Description: Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2130R-A680

Anti-Ki-67 Proliferation Marker Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-2130R-A680)
Supplier: Bioss
Description: Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5863R-A680

Anti-ADAMTSL3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-5863R-A680)
Supplier: Bioss
Description: Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM: 1 * 100 µl
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Anti-ADAMTSL3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5863R-CY3)
Supplier: Bioss
Description: Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM: 1 * 100 µl
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Anti-ADAMTSL3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5863R-CY5.5)
Supplier: Bioss
Description: Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9717R-A647

Anti-NID2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-9717R-A647)
Supplier: Bioss
Description: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl
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Anti-IgG Llama Polyclonal Antibody (CF™ 594)

Supplier: Biotium
Description: Llama anti-rabbit CF™ dye conjugates are prepared by labeling affinity purified llama anti-rabbit IgG (H+L) with a selection of CF™ dyes. CF™ dyes offer combined advantages in brightness, photostability, and specificity compared other fluorescent dyes. CF™594 (Ex/Em 593/614 nm) is a deep-red dye spectrally similar to Alexa Fluor® 594 and Texas Red® dye but yields much brighter protein conjugates due to its high quantum yield and exceptional water solubility. CF™594 also has excellent photostability ideal for demanding applications, such as confocal microscopy and single molecule imaging.

Alexa Fluor® and Texas Red® are registered trademarks of Thermo Fisher Scientific.

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Propenyl-L-NIO hydrochloride

Catalog Number: (ENZOALX270497M025)
Supplier: ENZO LIFE SCIENCES
Description: Potent, selective inhibitor of iNOS (NOS II). The Ki values for inhibition of iNOS (NOS II), nNOS (NOS I), and eNOS (NOS III) by ENIPO are 17, 10.3 and 58.2 µm, respectively, as determined using initial rate binding kinetics. However, ENIPO is a time-dependent inhibitor that, with longer incubations, demonstrates reversible tight binding inhibition that is selective for iNOS (NOS II) over nNOS (NOS I) or eNOS (NOS III). This selectivity results from iNOS (NOS II) exhibiting a 4-fold faster binding and 10-fold slower dissociation with ENIPO compared to nNOS (NOS I). Ki values for ENIPO binding to iNOS (NOS II) and nNOS (NOS I) are 0.56 and 6 µm, respectively. Accurate determination of the Ki value of ENIPO for eNOS (NOS III) has not been determined but is expected to be 50-fold less than iNOS (NOS II).
UOM: 1 * 25 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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