Zinc protoporphyrin ≥95% (by TLC)
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate, Protoporphyrin IX zinc(II), Zinc (II) Protoporphyrin IX
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.
- Heme oxygenase inhibitor
Dark solid.
Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures.
Formula:
C₃₄H₃₂N₄O₄Zn MW: 626,034 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00011612 CAS Number: 15442-64-5 |
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