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Supplier: ENZO LIFE SCIENCES
Description: MMP inhibitor

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Catalog Number: (ENZOBMLPI1080100)
Supplier: ENZO LIFE SCIENCES
Description: Highly specific, cell permeable, and irreversible 20S proteasome inhibitor. Inhibits ubiquitin proteasome pathway in cell culture (IC50=1µM). It has been suggested that the natural product lactacystin acts as a precursor for clasto-lactacystin β-lactone and that the latter is the sole species that interacts with the proteasome. Inhibits cathepsin A. Leads to a reduction of adipogenesis. Induces neurite growth and inhibits cell cycle progression. 
UOM: 1 * 100 µG

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Supplier: ENZO LIFE SCIENCES
Description: MG-132 is a potent, cell permeable and selective proteasome inhibitor (Ki = 4 nM).1 It inhibits NF-κB activation by preventing IκB degradation (IC50 = 3 μM). The peptide blocks degradation of short-lived proteins, which in turn induces HSP and ER chaperone expression, leading to thermotolerance (1 μM MG-132, 2 h.). It also stimulates neurite outgrowth in PC12 cells (20 nM optimal). The peptide has also been reported to increase the survival rate of mesenchymal stem cells following their transplantation. IC50’s for inhibition of Suc-LLVY-AMC and Z-LLL-AMC cleaving activities of proteasome were 0,85 and 0,1 μM respectively. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems, thus blockade of UPS by MG-132 activates autophagy.

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Catalog Number: (ENZOBMLPI1340001)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of TNF-alpha processing
UOM: 1 * 1 mg

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Catalog Number: (ENZOBMLPI1210200)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of trypsin and trypsin-like proteases
UOM: 1 * 200 mg

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Catalog Number: (ENZOBMLPI1350001)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of TNF-alpha processing
UOM: 1 * 1 mg

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Catalog Number: (ENZOBMLSE3600010)
Supplier: ENZO LIFE SCIENCES
Description: Produced in E. coli. Active recombinant matrix metalloproteinase-9 (MMP-9, gelatinase B, 92 kDa type IV collagenase) cloned from human cDNA.
UOM: 1 * 10 µG

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Catalog Number: (ENZOBMLSE4130005)
Supplier: ENZO LIFE SCIENCES
Description: Produced in insect cells.
UOM: 1 * 5 µG

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Catalog Number: (ENZOBMLSE2840100)
Supplier: ENZO LIFE SCIENCES
Description: Isolated from human neutrophils. Active enzyme.
UOM: 1 * 100 µG

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Catalog Number: (ENZOBMLSE3670010)
Supplier: ENZO LIFE SCIENCES
Description: Produced in insect cells. Full length glycosylated human procathepsin K.
UOM: 1 * 10 µG

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Catalog Number: (ENZOBMLSE3290010)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>. Active Matrix Metalloproteinase-10 (MMP-10, stromelysin-2, transin-2) catalytic domain from human cDNA.
UOM: 1 * 10 µG

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Catalog Number: (ENZOBMLSE3660050)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>. Full length human CDC25C.
UOM: 1 * 50 µG

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Catalog Number: (ENZOBMLSE3250001)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 1 mg

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Catalog Number: (ENZOBMLSE3230100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 100 µG

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Catalog Number: (ENZOBMLSE2385000)
Supplier: ENZO LIFE SCIENCES
Description: Produced in yeast. Recombinant human granzyme B (aa 21-247).
UOM: 1 * 1 Vial

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Catalog Number: (ENZOBMLSE2110025)
Supplier: ENZO LIFE SCIENCES
Description: High purity industry standard substrate for deubiquitinylating enzymes (DUBs).
UOM: 1 * 25 µG

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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