You Searched For: ENZO LIFE SCIENCES

Supplier: ENZO LIFE SCIENCES

Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

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Supplier: ENZO LIFE SCIENCES

Description: Anti-HSP25 + HSP27 Rabbit Polyclonal Antibody

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Supplier: ENZO LIFE SCIENCES

Description: The Hsp70 family of heat shock proteins contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

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Catalog Number: (ENZOENZABS2110100)

Supplier: ENZO LIFE SCIENCES

Description: Recommended Applications: Flow Cytometry, IHC (FS)

Species reactivity: Human, Sheep

UOM: 1 * 100 µG

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Catalog Number: (ENZOENZABS2040200)

Supplier: ENZO LIFE SCIENCES

Description: Recommended Applications: IHC, WB

Species reactivity:

UOM: 1 * 200 µl

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Catalog Number: (ENZOENZABS1680100)

Supplier: ENZO LIFE SCIENCES

Description: Recommended Applications: Flow Cytometry, IF, IHC (FS)

Species reactivity: Human, Sheep

UOM: 1 * 100 µG

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Catalog Number: (ENZOENZABS2310100)

Supplier: ENZO LIFE SCIENCES

Description: Recommended Applications: IHC (PS), IP

Species reactivity: Human, Dog

UOM: 1 * 100 µG

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Catalog Number: (ENZOENZABS2480100)

Supplier: ENZO LIFE SCIENCES

Description: Recommended Applications: Flow Cytometry, FUNC

Species reactivity: Human

UOM: 1 * 100 µG

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Catalog Number: (ENZOENZABS2330100)

Supplier: ENZO LIFE SCIENCES

Description: Recommended Applications: Flow Cytometry, IHC (FS), IP

Species reactivity: Human

UOM: 1 * 100 µG

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Supplier: ENZO LIFE SCIENCES

Description: CDK inhibitor

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Catalog Number: (ENZOBPDABS029011)

Supplier: ENZO LIFE SCIENCES

Description: Peptide tyrosine-tyrosine (PYY) amide is a 36 amino-acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides, and inhibits gall bladder secretion, gut motility and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.

UOM: 1 * 1 mg

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Supplier: ENZO LIFE SCIENCES

Description: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

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Supplier: ENZO LIFE SCIENCES

Description: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

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Supplier: ENZO LIFE SCIENCES

Description: GroEL and GroES are <i>E. coli</i> chaperonins, which are homologs of mitochondrial chaperonins Hsp60 and Hsp10. GroEL is a double toriodal assembly of 14 identical subunits which form two heptameric rings stacked back-to-back, with a cavity at each end. GroEL and its co-chaperonin GroES facilitate protein folding with an ATP-dependent mechanism.

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Supplier: ENZO LIFE SCIENCES

Description: Farnesyltransferase inhibitor

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Supplier: ENZO LIFE SCIENCES

Description: HMG-CoA reductase inhibitor

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