Description: Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.

Catalog Number: ENZOALX260089M005

UOM: 1 * 5 mg

Supplier: ENZO LIFE SCIENCES

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Description: TRP channel agonist.

Catalog Number: ENZOALX550396M005

UOM: 1 * 5 mg

Supplier: ENZO LIFE SCIENCES

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Description: For the detection of apoptotic cells by flow cytometry.

Catalog Number: ENZOALX850020KI02

UOM: 1 * 100 Tests

Supplier: ENZO LIFE SCIENCES

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Description: Positively charged rhodamine dyes (such as rhodamine esters and rosamines) are selectively localized in mitochondria, thus they are widely used for labeling mitochondria of live cells. Like JC-1,TMRE is widely used for measuring mitochondrial membrane potential, in addition to selectively staining mitochondria. Real-time imaging of mitochondrial membrane potential in individual cardiomyocytes within perfused rat hearts has been demonstrated with this dye, using 2-photon laser-scanning microscopy.

Catalog Number: ENZOENZ52309

UOM: 1 * 25 mg

Supplier: ENZO LIFE SCIENCES

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Description: Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to provide prognostic information in breast, prostate, colon, and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

Catalog Number: ENZOALX210309R100

UOM: 1 * 100 µl

Supplier: ENZO LIFE SCIENCES

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Description: Inhibitor of caspase-1 and -4

Catalog Number: ENZOALX260016M001

UOM: 1 * 1 mg

Supplier: ENZO LIFE SCIENCES

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Description: Potent and selective serotonin uptake inhibitor

Catalog Number: ENZOBMLNS1400250

UOM: 1 * 250 mg

Supplier: ENZO LIFE SCIENCES

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Description: Produced in <i>E. coli</i>.

Catalog Number: ENZOALX201047U100

UOM: 1 * 1 Vial

Supplier: ENZO LIFE SCIENCES

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Description: Recommended Applications: IF

Species reactivity: Human, Dog

Catalog Number: ENZOENZABS2500100

UOM: 1 * 100 µG

Supplier: ENZO LIFE SCIENCES

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Description: Apoptosis inducer.

Catalog Number: ENZOALX420035M005

UOM: 1 * 5 mg

Supplier: ENZO LIFE SCIENCES

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Description: CD51 (integrin αV subunit) associates with CD61 (integrin β3 subunit) binding to the RGD sequence in extracellular matrix proteins like vitronectin, fibrinogen, thrombospondin, von Willebrand factor and osteopontin. The αV/β3 heterodimer is expressed in endothelial cells, leukocytes, NK cells, macrophages, neutrophils, platelets and several malignant tumor cells and seems to play a role in embryo implantation, angiogenesis, wound healing and cancer. αV/β3  is also highly expressed in osteoclasts being important for bone resorption.

Catalog Number: ENZOALX210537R100

UOM: 1 * 100 µl

Supplier: ENZO LIFE SCIENCES

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Description: Prostanoid receptor ligand.

Catalog Number: ENZOBMLPG0050010

UOM: 1 * 10 mg

Supplier: ENZO LIFE SCIENCES

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Description: Produced in <i>E.coli</i>.

Catalog Number: ENZOADI908066010

UOM: 1 * 10 µG

Supplier: ENZO LIFE SCIENCES

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Description: Produced in HEK 293 cells. The cysteine-rich domain of human NGFR (nerve growth factor receptor; p75NTR) (aa 1-250) is fused to the Fc portion of human IgG1.

Catalog Number: ENZOALX522044C050

UOM: 1 * 50 µG

Supplier: ENZO LIFE SCIENCES

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Description: Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.

Catalog Number: ENZOBMLEI1080100

UOM: 1 * 100 mg

Supplier: ENZO LIFE SCIENCES

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Description: Anti-HSP90 Mouse Monoclonal Antibody [clone: 2D11B9]

Catalog Number: ENZOADISPA831200

UOM: 1 * 200 µG

Supplier: ENZO LIFE SCIENCES

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