Pioglitazone ≥97% (by HPLC)
Supplier: ENZO LIFE SCIENCES AG
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Warning
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Synonyms:
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
PPARgamma activator.
Pioglitazone selectively activates PPARγ-1. It is about one tenth as potent as rosiglitazone (EC₅₀~500 nM for human and mouse PPARγ). In a transactivation assay using COS-1 cells transfected with full length human PPARα and RXRα, pioglitazone and rosiglitazone exhibit low level activation of PPARα at 1 µM and 5.4- and 4.2-fold activation, respectively, at a concentration of 10 µM.
Soluble in DMSO (2.5 mg/ml) or dimethyl formamide (2.5 mg/ml).
Formula:
C₁₉H₂₀N₂O₃S MW: 356,44 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00865504 CAS Number: 111025-46-8 |
Specification Test Results
Purity | ≥97% (HPLC) |
Identity | Confirmed by ¹H-NMR |
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