Indirubin ≥98% (by 1H-NMR, HPLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: Indigo Red, [2,3'-Biindolinylidene]-2',3-dione

ALX270361M001 ALX270361M005
ENZOALX270361M001EA 77.1 GBP
ENZOALX270361M001 ENZOALX270361M005
Indirubin ≥98% (by 1H-NMR, HPLC)
Indirubin

Inhibitor of CDK and GSK


Inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) and of GSK-3beta (IC50=600nM). Inhibits inflammatory reaction in delayed-type hypersensitivity in mice. Ligand of human aryl hydrocarbon receptor. Exhibits anti-cancer activity.


Synthetic.

Formula: C₁₆H₁₀N₂O₂
MW: 262,27 g/mol
MDL Number: MFCD00221745
CAS Number: 479-41-4

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