Toluene-α-sulphonyl fluoride ≥99% (by GC-FID)

Supplier: ENZO LIFE SCIENCES AG
Danger

Synonyms: α-Toluenesulphonyl fluoridePMSFPhenylmethylsulphonyl fluoridePhenylmethanesulphonyl fluoride

ENZOALX270184G025EA 242 GBP
ENZOALX270184G025 ENZOALX270184G005
Toluene-α-sulphonyl fluoride ≥99% (by GC-FID)
Toluene-α-sulphonyl fluoride

Irreversible inhibitor of serine proteases. Widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity. Spleen membranes used for CB2 studies do not require this pretreatment, as FAAH activity is absent in these cells. Inhibits also cysteine proteases like papain (reversible by DTT treatment, as well as internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor see AEBSF.


  • Inhibitor of serine proteases and FAAH


White to off-white needle crystals.


Soluble in 100% ethanol, methanol or isopropanol; insoluble in water.

Formula: C₇H₇FO₂S
MW: 174,2 g/mol
Boiling Pt: 80…85 °C (0,3 mmHg)
Melting Pt: 91…92 °C
Storage Temperature: Ambient
MDL Number: MFCD00007424
CAS Number: 329-98-6
EINECS: 206-350-2
UN: 2923
ADR: 8,III

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