GW5074 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
BMLEI3070005
BMLEI3070025
ENZOBMLEI3070005EA
111
GBP
ENZOBMLEI3070005
ENZOBMLEI3070025
GW5074 ≥98% (by TLC)
GW5074
Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.
- Raf inhibitor
Yellow to orange solid.
Soluble in DMSO (>25 mg/ml).
Formula:
C₁₅H₈Br₂INO₂ Storage Temperature: Freezer |
MDL Number:
MFCD09971042 CAS Number: 220904-83-6 |
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