Gabexate mesylate ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid ethyl ester Mesylate, Ethyl 4-((6-guanidinohexanoyl)oxy)benzoate methanesulphonate, Gabexate Methanesulphonate

BMLPI1440010 BMLPI1440050
ENZOBMLPI1440010EA 81.1 GBP
ENZOBMLPI1440010 ENZOBMLPI1440050
Gabexate mesylate ≥98% (by HPLC)
Gabexate mesylate

A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis.


  • Protease inhibitor


White solid.


Soluble in water (25 mg/ml).

Formula: C₁₆H₂₃N₃O₄·CH₃SO₃H
MW: 417,5 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00210299
CAS Number: 56974-61-9
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=00639d19f24fb21bb7818076610e72d9744d8e68&vid=fe6afd23d45db691f54b97b16619e333dec1beb3&prid=web&clid=SAPDAM

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR