ML-9 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
1-(5-Chloronaphthalene-1-sulphonyl)-1H-hexahydro-1,4-diazepine hydrochloride, 1-((5-Chloronaphthalen-1-yl)sulphonyl)-1,4-diazepane hydrochloride
Selective inhibitor of MLC kinase (Ki=3.8 µM). Inhibits insulin-stimulated 2-deoxyglucose transport and PP-1 activation in adipocytes, possibly via an effect on MAP kinase or its activation. Useful PKB inhibitor (IC50=10-50 µM). Also known to inhibit PKA (IC50=20 µM) and S6 kinase (IC50=50 µM). Does not inhibit PI 3-kinase.
- Myelin basic protein inhibitor
White solid.
Soluble in DMSO (10mg/ml) and ethanol/water (1:1, 10mg/ml).
Formula:
C₁₅H₁₇N₂O₂SCl·HCl MW: 361,3 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00065525 CAS Number: 105637-50-1 |
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