SC-514 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 4-amino-[2,3'-bithiophene]-5-carboxamide, IKK-2 Inhibitor, SC-514

BMLEI3430010 BMLEI3430050
ENZOBMLEI3430010EA 101 GBP
ENZOBMLEI3430010 ENZOBMLEI3430050
SC-514 ≥98% (by TLC)
SC-514

IKK inhibitor


Selective, reversible and ATP-competitive inhibitor of IKK2 (IC50=11.2µM). Does not inhibit other IKK isoforms or other serine/threonine or tyrosine kinases. Inhibits transcription of NF-κB dependent genes in IL-1β-induced rheumatoid arthritis-derived synovial fibroblasts in a dose-dependent fashion.

Formula: C₉H₈N₂OS₂
MW: 224,3 g/mol
MDL Number: MFCD00206459
CAS Number: 354812-17-2
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