IQ-1 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
BMLWN1150005
BMLWN1150025
ENZOBMLWN1150005EA
115
GBP
ENZOBMLWN1150005
ENZOBMLWN1150025
IQ-1 ≥98% (by TLC)
IQ-1
Disrupts Wnt signaling
IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription. Upregulates expression of Oct4 and Sox2 transcription factors.
Formula:
C₂₁H₂₂N₄O₂ |
MDL Number:
MFCD00354369 CAS Number: 331001-62-8 |
|
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