N-Acetyl-S-geranylgeranyl-L-cysteine ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: AGGC

BMLG2200005 BMLG2200025
ENZOBMLG2200005EA 106 GBP
ENZOBMLG2200005 ENZOBMLG2200025
N-Acetyl-S-geranylgeranyl-L-cysteine ≥98% (by TLC)
N-Acetyl-S-geranylgeranyl-L-cysteine

Blocks methyl esterification of geranylgeranylated proteins


AGGC specifically blocks methyl esterification of geranylgeranylated proteins such as Rab proteins. AGGC blocks receptor-mediated signal transduction in human neutrophils (IC50=4 µM). Induces insulin release from HIT-T15 cells by mimicking the action of Rab3A and inhibits beta2-integrin-induced actin polymerization (IC50~45 nM) in neutrophils.

CAS Number: 139332-94-8
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=a525de60296a64d0540cd1e2c6f82f82d0a26844&vid=d98fc51fa6f43f1ce369f45fbbd12e841849eefd&prid=web&clid=SAPDAM

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