PD-0173074 ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
PD 173074, 1-(tert-Butyl)-3-[7-[[4-(diethylamino)butyl]amino]-3-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-2-yl]urea, PD173074, 1-(tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea
Cell-permeable, potent inhibitor of FGF and VEGF receptors.
A cell-permeable compound that acts as a potent, ATP-competitive, and reversible inhibitor of FGF and VEGF receptors. PD 173074 inhibits PDGFR and c-Src only at much higher concentration. Shown to inhibit the autophosphorylation of endogenous FGFR1 and overexpressed VEGFR2.
Formula:
C₂₈H₄₁N₇O₃ MW: 523,7 g/mol |
MDL Number:
MFCD08705327 CAS Number: 219580-11-7 |
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