Butyrolactone I ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES AG

BMLCC2100200 BMLCC2101000
ENZOBMLCC2100200EA 123 GBP
ENZOBMLCC2100200 ENZOBMLCC2101000
Butyrolactone I ≥99% (by TLC)
Butyrolactone I

CDK inhibitor


Cell permeable and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. G1/S and G2/M transitions, in W138 cells, were inhibited, concurrent with inhibition of the phosphorylations of, respectively, retinoblastoma protein and histone H1. It is an important tool for probing the cellular roles of CDKs. Blocks Fas-induced apoptosis. Displays antitumor activity.

Formula: C₂₄H₂₄O₇
MDL Number: MFCD03453074
CAS Number: 87414-49-1
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