PP2 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 1-(tert-Butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

BMLEI2970001 BMLEI2970005
ENZOBMLEI2970001EA 101 GBP
ENZOBMLEI2970001 ENZOBMLEI2970005
PP2 ≥98% (by TLC)
PP2

Src kinase inhibitor


A potent and selective inhibitor of the Src family tyrosine kinases. Inhibits Lck (IC50=4 nM), Fyn (IC50=5 nM), and Hck (IC50=5 nM). It displays weaker inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50 100 µM) and JAK2 (IC5050 µM). PP2 is a useful tool for probing the involvement of Src family tyrosine kinases in cellular signaling.

Formula: C₁₅H₁₆ClN₅
MW: 301,8 g/mol
MDL Number: MFCD01568210
CAS Number: 172889-27-9
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