U-18666A ≥99%

Supplier: ENZO LIFE SCIENCES AG

BMLS2000010 BMLS2000050
ENZOBMLS2000010EA 120 GBP
ENZOBMLS2000010 ENZOBMLS2000050
U-18666A ≥99%
U-18666A

Oxido-squalene cyclase inhibitor


A useful tool for inhibition of cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum. Inhibits cholesterol transport in a variety of cell types such as macrophages and sympathetic neurons. May be used to induce a Neimann-Pick disease type C (NPC)or NPC-like phenotype in a variety of cell types. Inhibits cholesterol biosynthesis at the level of oxido-squalene cyclase (OSC). Induction of cataracts is a common toxic feature of OSC inhibitors such as U18666A.

Formula: C₂₅H₄₂ClNO₂
MW: 424,066 g/mol
MDL Number: MFCD00210908
CAS Number: 3039-71-2
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