β-Lapachone ≥98%

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 2,2-Dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione

BMLGR3080005 BMLGR3080025
ENZOBMLGR3080005EA 79.1 GBP
ENZOBMLGR3080005 ENZOBMLGR3080025
β-Lapachone ≥98%
beta-Lapachone

Topoisomerase inhibitor


Novel DNA topoisomerase I inhibitor. Unlike camptothecin, beta-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1.

Formula: C₁₅H₁₄O₃
MW: 242,274 g/mol
MDL Number: MFCD01712233
CAS Number: 4707-32-8
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