Isobaric labelling reagent set, iodoTMTsixplex™

Supplier: Thermo Fisher Scientific

90101 90102
PIER90101EA 921 GBP
PIER90101 PIER90102
Isobaric labelling reagent set, iodoTMTsixplex™
Protein Linking and Labeling Systems

The iodoTMTsixplex™ labelling reagents enable concurrent identification and multiplexed quantitation of proteins in different samples using tandem mass spectrometry.


  • Specificaly reacts only with sulfhydryl groups (reduced, unmodified cysteine residues)
  • Labelled proteins and peptides are not susceptible to reducing agents
  • Flexible for both duplex isotopic and sixplex isobaric quantitation of protein
  • Can be used to study cysteine modifications (eg. di-sulphide bridges, S-nitrosylation)


The iodoTMT™ reagents are sets of isobaric (mass and structure) isomers that are iodoacetyl-activated for covalent, irreversible labeling of sulphhydryl (—SH) groups. They can be differentiated by mass spectrometry (MS), enabling quantitation of the relative abundance of cysteine modifications, such as S-nitrosylation, oxidation and disulfide bonds, in cultured cells grown or treated with different conditions.


Delivery information: The reagent set includes 0,2 mg or 5×0,2 mg of iodoTMT6-126 label reagent, iodoTMT6-127 label reagent, iodoTMT6-128 label reagent, iodoTMT6-129 label reagent, iodoTMT6-130 label reagent and iodoTMT6-131 label reagent.

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