Carboxyl reactive biotin reagents, HOOK™

Supplier: G Biosciences

BG-16 BG-17
BG-16EA 776 GBP
BG-16 BG-17
Carboxyl reactive biotin reagents, HOOK™
Protein Linking and Labeling Systems

HOOK™ Biotin-PEG₂-Amine, and its long chain form, HOOK™ Biotin-PEG₃-Amine, are carboxyl reactive biotinylation reagents. These agents contain terminal amines and react with carboxyl groups found at the carboxyl termini, aspartate, and glutamate side chains. The reaction is mediated by a water-soluble carbodiimide (EDC). The carbodiimide activates the carboxyl group and reacts with the amines (-NH₂) on the biotinylation agent to form an amide bond. This reaction is rapid and takes just a few minutes to complete. Under these conditions, hydrazide-derivatives of biotin reagents may also react with the carboxyls.

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