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Image Unavailable-BOSSBS-4098R-A680

Anti-CARM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.
Catalog Number: BOSSBS-4098R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-CCDL928276

Hydrogen and High Purity Air Generator for GC-FID

Description: Generator that produces all necessary gasses required to run the Lucidity GC-FID.
Catalog Number: CCDL928276
UOM: 1 * 1 items
Supplier: LUCIDITY
Product Image-BARN7405

CryoPlus™ Sample Storage Systems

Description: <p><span style="color:black">Increase valuable laboratory storage space with CryoPlus™ Storage Systems, which store up to 38500 vials (2,0 ml). The ideal combination of liquid nitrogen, storage reliability and microprocessor technology, the CryoPlus series LN₂ storage system provides precise and accurate control over all parameters without complicated programming.</span></p>
Catalog Number: BARN7405
UOM: 1 * 1 items
Supplier: Thermo Fisher Scientific

New Product


Product Image-WTWA252018

Cuvette tests for water testing for WTW spectrophotometers and photometers

Description: A wide choice of tests is available, for routine quantitative analysis in different applications, designed for use with WTW spectrophotometers and photometers. The test is automatically recognised by the laboratory instruments (via a barcoding system) and results are displayed in the appropriate units. Due to the different photometer optics, one test may yield different measuring ranges in different instruments; LED photometers may have smaller measuring ranges for the same test.
Catalog Number: WTWA252018
UOM: 1 * 25 Tests
Supplier: WTW
Product Image-ORIOCODM150

Orion™ AQUAfast™ Reaction/Digestion Tubes and Liquid Reagents

Description: Use Thermo Scientific™ Orion™ AQUAfast digestion tubes, reaction tubes and liquid reagents with Orion™ AQUAfast colorimeters and Thermo Scientific™ Orion™ AquaMate Vis and UV-Vis spectrophotometers. Digestion and reaction tubes contain the precise amount of reagent, are made of special optical glass and fit the Orion™ AQUAfast COD165 thermoreactor. Digestion tubes measure COD, total nitrogen and total phosphate. Reaction tubes measure ammonia, nitrate and phosphate. Liquid reagents mix quickly and easily in solution and measure fluoride (SPADN), hydrazine and pH.
Catalog Number: ORIOCODM150
UOM: 1 * 1 SET
Supplier: Thermo Orion
Product Image-444-7036

VWR® Stainless Steel Media Bottle Clamps

Description: Clamp, Clamps for media bottles, stainless steel, VWR®, Stainless steel, For: 500 ml
Catalog Number: 444-7036
UOM: 1 * 1 items
Supplier: VWR Collection
Product Image-DRAE8103661

Gas detection tubes for nitrous fumes

Description: To measure the 'spot concentrations' of nitrous fumes for use with an Accuro® pump. Uses include determination and measurement of concentration peaks, personal exposure in the inhalation area, detection of leaks in pipelines or gas installations, air analysis in sewers, shafts and confined spaces.
Catalog Number: DRAE8103661
UOM: 1 * 10 items
Supplier: Dräger

Certificates


Image Unavailable-VWRL080211

VWR®, Jars, Glass

Description: These jars are made of glass with PP cap.
Catalog Number: VWRL080211
UOM: 1 * 40 items
Supplier: LAB3 OWN PRODUCTION
Product Image-241-0032

VWR®, Clamps

Description: Laboral aluminium alloy.
Catalog Number: 241-0032
UOM: 1 * 2 items
Supplier: VWR Collection
Product Image-115-0202

VWR®, Wipes for General Applications

Description: Absorbent, soft, thick, low lint tissues made from virgin fibres. For light use in the laboratory, electronics, computer industry, pharmaceuticals, biotechnology and optics.
Catalog Number: 115-0202
UOM: 1 * 280 items
Supplier: VWR Collection
Product Image-478-0730

Dewar vessels, cylindrical, type C and G-C

Description: Dewar vessel, in silvered borosilicate glass, blue coated metal protective covering. For storage of liquid nitrogen, dry ice and other coolants.
Catalog Number: 478-0730
UOM: 1 * 1 items
Supplier: KGW
Product Image-PRSI7219

Anti-CARM1 Rabbit Polyclonal Antibody

Description: CARM1 Antibody: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-κB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.
Catalog Number: PRSI7219
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-KIMB7400

Wipes for general applications, WYPALL* L20

Description: These high-capacity, single-use paper wipers are excellent for Large spills. They are also ideal for parts and tool cleanups, mining operations maintenance, hydraulic leak absorption, general-purpose field utility wiping, conveyor and roller cleaning, and retail store maintenance and cleaning.
Catalog Number: KIMB7400
UOM: 1 * 280 items
Supplier: KIMBERLY CLARK
Product Image-GAINA4CL-12T1-WH

Permanent Cryogenic Labels for Laser Printers

Description: Permanent cryogenic laser labels for long-term storage in liquid phase and vapor phase liquid nitrogen (−196 °C), lab freezers (−80 °C), and on dry ice. Supplied in A4 sheet format for printing in standard desktop laser printers, these cryogenic labels do not jam printers and withstand UV and gamma irradiation.
Catalog Number: GAINA4CL-12T1-WH
UOM: 1 * 2.560 items
Supplier: GA
Product Image-662-2362

Standards, calibration for LCK cuvettes, Addista

Description: System for Analytical Quality Assurance (AQA), consisting of one combined standard/spiking solution and two round robin test solutions.
Catalog Number: 662-2362
UOM: 1 * 1 KIT
Supplier: Hach
Product Image-705-0709

Thermoreactors, CR series

Description: Thermoreactors for the determination of COD, total nitrogen or total phosphorus, ensure complete digestion of the sample and maintain the necessary high reaction temperature throughout the defined period. The most important temperatures and digestion times are stored in 8 fixed, easily selectable digestion programmes. CR 3200 and CR 4200 can be used with optional TFK CR external temperature probe, which can be used as a testing aid. It can be plugged into the interface in place of a cuvette, the set and actual temperatures can be output to either a printer or a PC, so function can not only be monitored, but also documented. Suitable for 16 mm cuvettes.
Catalog Number: 705-0709
UOM: 1 * 1 items
Supplier: WTW
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