You Searched For: ENZO LIFE SCIENCES

Catalog Number: (ENZOADI907001)

Supplier: ENZO LIFE SCIENCES

Description: A complete kit for the labeling of antibodies, proteins, peptides, and nucleic acids with Acridinium NHS Ester.

UOM: 1 * 1 KIT

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Catalog Number: (ENZOADI907026)

Supplier: ENZO LIFE SCIENCES

Description: For the measurement of acetyl-CoA dependent acetyltransferase activity in purified in vitro samples that do not contain reductants from any species.

UOM: 1 * 1 KIT

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Catalog Number: (ENZOADIAAP426E)

Supplier: ENZO LIFE SCIENCES

Description: TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NF-κB.

UOM: 1 * 100 µl

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Supplier: ENZO LIFE SCIENCES

Description: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Supplier: ENZO LIFE SCIENCES

Description: Anti-TAPBP Rabbit Polyclonal Antibody

Catalog Number: (ENZOADIAAP460E)

Supplier: ENZO LIFE SCIENCES

Description: The RICK (Receptor-interacting serine/threonine protein kinase 2) protein, also known as RIP-like interacting CLARP kinase, and CARD-containing ICE associated kinase, contains an N-terminal kinase domain and a C-terminal CARD domain.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADICSA614E)

Supplier: ENZO LIFE SCIENCES

Description: The chromatin non-histone high mobility group of proteins (HMG)-1 and -2 contain conserved domains known as HMG-boxes. Both HMG-1 and HMG-2 contain an N-terminal HMG box, a central HMG box and an acidic carboxy terminus.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI905629100)

Supplier: ENZO LIFE SCIENCES

Description: Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to provide prognostic information in breast, prostate, colon, and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI905618100)

Supplier: ENZO LIFE SCIENCES

Description: The GST superfamily of enzymes play an important role in detoxification of xenobiotics by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. There are four main GST classes; alpha, mu, pi, and tau. GST-P is a member of the pi class of GSTs, and its expression is specifically increased in the early stages of rat hepatocarcinogenesis. Due to its high affinity for glutathione, GST is frequently utilized as an approximately 26 kDa fusion tag for the expression and purification of recombinant proteins.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI905630100)

Supplier: ENZO LIFE SCIENCES

Description: Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to provide prognostic information in breast, prostate, colon, and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI905249100)

Supplier: ENZO LIFE SCIENCES

Description: TNF-alpha converting enzyme (TACE) is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), and is responsible for the cleavage of membrane-bound precursor TNF-alpha to its mature, secreted form. TACE also processes other cell surface proteins, including TNF receptor, TGFalpha, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP).

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI905619100)

Supplier: ENZO LIFE SCIENCES

Description: The exotoxin produced by B. anthracis is composed of three proteins: a cell-receptor binding protein known as Protective Antigen (PA), and two enzymes, Edema Factor (EF) and Lethal Factor (LF). An 83 kDa form of PA binds to a cell surface receptor and, upon proteolytic activation to a 63 kDa fragment, heptamerizes to form a membrane channel that mediates the entry of three molecules of LF or EF into the cells. PA and LF form Lethal Toxin, which is the dominant virulence factor produced by B. Anthracis and is the major cause of death in infected animals.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI905710100)

Supplier: ENZO LIFE SCIENCES

Description: The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.

UOM: 1 * 100 µG

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Catalog Number: (ENZOADI960076)

Supplier: ENZO LIFE SCIENCES

Description: Most comprehensive portfolio of heat shock protein (chaperone) products commercially available.

UOM: 1 * 1 SET

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Supplier: ENZO LIFE SCIENCES

Description: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Catalog Number: (ENZOADIAAM140E)

Supplier: ENZO LIFE SCIENCES

Description: Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterised by the presence of atleast one Bcl-2 homology (BH) domains.

UOM: 1 * 100 µG

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