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Catalog Number: (ENZOBMLPD1770005)
Supplier: ENZO LIFE SCIENCES
Description: R-enantiomer of rolipram which is more active at inhibition of PDE IV, Ki=06 µM. 10-fold more active than S-rolipram at inhibition of PDE IV. Inhibits antigen-induced contraction of guinea-pig colonic smooth muscle, EC50=0.1 µM.
UOM: 1 * 5 mg


Supplier: ENZO LIFE SCIENCES
Description: FP receptor agonist.

Supplier: ENZO LIFE SCIENCES
Description: Thromboxane A2 antagonist and TXA2 synthase inhibitor

Supplier: ENZO LIFE SCIENCES
Description: P62, also known as Sequestosome I, is a 62kDa, 440 amino acid protein, initially identified as a ligand of the SH2 domain of p56lck, now known to be expressed in many tissues. In addition to TRAF6, PEST and zinc finger motifs, p62 has a C-terminal ubiquitin binding association (UBA) domain with an affinity for multi-ubiquitin chains, and it is considered to serve as a scaffold protein, capable of binding to multiple signalling molecules and uniting receptor-mediated signalling events with ubiquitinylation. Elevated levels of p62 have been reported in breast tumours and in alcoholic liver disease where p62 has been shown to be involved in the formation of Mallory bodies. Several mutations in the p62 UBA domain have been identified and the etiology of Paget’s disease of bone has been linked to one such mutation. Kuusisto and colleagues have demonstrated that p62 is also present in elevated levels in the hallmark inclusions found in various neurodegenerative conditions, including tauopathies (Alzheimer’s disease, Picks disease, and frontotemporal dementia) and synucleinopathies (Parkinson’s disease, dementia with Lewy body disease and multiple system atrophy). In recent years ubiquitin immunostaining has been used to provide adjunct information for neuropathological diagnosis, but it is becoming evident that p62 may be an even more reliable marker of neurodegenerative disease inclusion detection than tau, alpha-synuclein or ubiquitin immunostaining.

Supplier: ENZO LIFE SCIENCES
Description: Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERP) is a membrane-associated ER protein strongly up-regulated by inducers of ER stress.

Supplier: ENZO LIFE SCIENCES
Description: Immunomodulator.

Catalog Number: (ENZOBMLRA1010010)
Supplier: ENZO LIFE SCIENCES
Description: Leukotriene D₄ antagonist
UOM: 1 * 10 mg


Catalog Number: (ENZOBMLUW07300050)
Supplier: ENZO LIFE SCIENCES
Description: Protein components produced in <i>E. coli</i>. Synthesised enzymatically in vitro.
UOM: 1 * 50 µG


Catalog Number: (ENZOBMLT1200050)
Supplier: ENZO LIFE SCIENCES
Description: A novel synthetic inhibitor of microtubule formation which binds to the colchicine site. It prevents the stabilization of microtubules in taxol-treated cells. Blocks the cell cycle in M-phase.
UOM: 1 * 50 mg


Supplier: ENZO LIFE SCIENCES
Description: Ultra-pure; inhibits actin polymerization

Catalog Number: (ENZOBMLUW05900001)
Supplier: ENZO LIFE SCIENCES
Description: This kit provides the means of generating a thioester-linked NEDD8-conjugated E2 enzyme, utilizing the first two steps in the NEDD8 cascade, for use in the NEDDylation of E3 ligases and target substrate proteins (user supplied). A NEDD8-specific antibody is provided for detection of NEDDylated proteins via SDS-PAGE and Western blotting.
UOM: 1 * 20 Tests


Catalog Number: (ENZOBMLUW00650025)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli </i>cells. Derivatised chemically, <i>in vitro</i>.
UOM: 1 * 25 µG


Catalog Number: (ENZOBMLUW09600100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 100 µG


Catalog Number: (ENZOBMLUW10100100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 100 µG


Supplier: ENZO LIFE SCIENCES
Description: Docetaxel is taxane-type antineoplastic agent structurally similar to taxol.

Catalog Number: (ENZOBMLT1080005)
Supplier: ENZO LIFE SCIENCES
Description: Ultra-pure; inhibits actin polymerization
UOM: 1 * 5 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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