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Image Unavailable-ENZOADIKAMCP100E

Anti-NCL Mouse Monoclonal Antibody [clone: 400]

Catalog Number: (ENZOADIKAMCP100E)
Supplier: ENZO LIFE SCIENCES
Description: Nucleolin (identical to human DNA helicase IV) is an abundant, non-ribosomal protein of the nucleolus involved in the organization of nuclear chromatin, rDNA transcription, packaging of pre-RNA, ribosome assembly, nucleocytoplasmic transport, cytokinesis, nucleogenesis, and apoptosis. A predominantly nuclear protein, the presence of nucleolin at the surface of cancer cells suggests that it could be valuable as a marker for the diagnosis of cancer.
UOM: 1 * 100 µG
Image Unavailable-ENZOBMLS1040005

Conduritol B epoxide ≥96% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: A potent, irreversible inhibitor of various plant β-glucosidases and mammalian glucocerebrosidase. Has been employed in in vitro and animal models for Gaucher’s disease. It raises intracellular levels of glucosylceramide by inhibiting glucosylceramidase.

Image Unavailable-ENZOALX804061C100

Anti-MAPK Mouse Monoclonal Antibody [clone: 12D4]

Catalog Number: (ENZOALX804061C100)
Supplier: ENZO LIFE SCIENCES
Description: Host: Mouse, Isotype: IgG1
UOM: 1 * 100 µG
Image Unavailable-ENZOENZ42844

Red 580 dUTP

Catalog Number: (ENZOENZ42844)
Supplier: ENZO LIFE SCIENCES
Description: Red 580 [5-ROX] dUTP can replace TTP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase. Fluorescently labelled probes can be prepared with this fluorescent nucleotide by a variety of methods including nick translation, random prime labelling, cDNA labelling and 3’-end labelling. Probes generated by these methods are suitable for use for the identification of specific sequences by in situ hybridization procedures on fixed cells and tissues by direct fluorescence detection. Red 580 dUTP can also be used for multicolor fluorescence labelling.
UOM: 1 * 25 Nmo
Product Image-ENZOALX804258L001

Anti-SNCA Rat Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: Synuclein was originally identified in Torpedo californica as a small neuroprotein that localized to the nuclear envelope of neurons and to presynaptic nerve termini. The human homolog was initially termed NACP, a precursor protein to NAC (Non-Ab Component), because of its prevalence in amyloid plaques in Alzheimer’s patients. Later, NACP was recognized as being alpha-Synuclein (alpha-SYN), a 14kDa protein, belonging to the synuclein family of phosphoproteins that also includes: betalpha-SYNuclein, gammalpha-SYNuclein, and synoretin.
alpha-SYN is recognized as a key component in the development and diagnosis of neurodegenerative synucleinopathic diseases (NSDs), such as Alzheimer’s and Parkinson’s disease. In the past five years, several genetic and post-translational modifications to alpha-SYN have been elucidated that have been linked to its collaboration in the formation of the classical Lewy bodies (LBs) or Lewy neurites that are associated with neurodegeneration. A study that shed more light on the neurogenesis of autorecessive synucleinopathies (ARSs) was the finding that alpha-SYN accumulation can occur due to mutations in the E3 ubiquitin ligase.
ARSs only account for a small percentage of NSD. Thus the illustration that alpha-SYN has a high susceptibility to tyrosine nitration may be the key component in understanding the formation of LBs. Due to the chemical structure of alpha-SYN, tyrosine nitration readily leads to the formation of oligomers via covalent O,O’-dityrosine bonds (cross-linking). Nitrosylated, wild-type, alpha-SYN products thus form SDS-insoluble, heat-stable aggregates in vitro that may account for alpha-SYN inclusions in all forms of NSDs.

Image Unavailable-ENZOBMLSL2260005

Myriocin ≥98% (by TLC)

Catalog Number: (ENZOBMLSL2260005)
Supplier: ENZO LIFE SCIENCES
Description: Palmitoyltransferase inhibitor
UOM: 1 * 5 mg
Image Unavailable-ENZOADI901051

15(S)-HETE ELISA kit

Catalog Number: (ENZOADI901051)
Supplier: ENZO LIFE SCIENCES
Description: For the quantitative determination of 15(S)-HETE in culture supernatants, plasma, serum, and urine from any species.
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLSE3220100

Human recombinant Tau-352 (0N3R variant) (from E. coli)

Catalog Number: (ENZOBMLSE3220100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 100 µG
Image Unavailable-ENZOBMLP3200001

IRS-1 (Tyr608) peptide

Catalog Number: (ENZOBMLP3200001)
Supplier: ENZO LIFE SCIENCES
Description: Insulin receptor substrate
UOM: 1 * 1 mg
Image Unavailable-ENZOBMLPI1120005

Prolyl endopeptidase inhibitor ≥97% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: A potent and selective inhibitor of prolyl endopeptidase (PEP/PREP/POP, EC 3.4.21.26). Ki=0.35 nM for mouse brain enzyme. Inhibits the cleavage of arginine-vasopressin, gonadotropin-releasing hormone, and other peptides.

Image Unavailable-ENZOBMLAK3100001

ADAM17 fluorometric drug discovery kit

Catalog Number: (ENZOBMLAK3100001)
Supplier: ENZO LIFE SCIENCES
Description: Designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide. The ADAM17 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide: Mca-PLAQAV-Dpa-RSSSR-NH2. Mca fluorescence is quenched by the Dpa group until cleavage by proteases separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of ADAM17, a potential therapeutic target. The compound GM6001 is also included as a prototypic control inhibitor.
UOM: 1 * 1 KIT
Product Image-ENZOALX350220M050

Cafestol ≥98% (by UHPLC)

Catalog Number: (ENZOALX350220M050)
Supplier: ENZO LIFE SCIENCES
Description: GST activator.
UOM: 1 * 50 mg
Image Unavailable-ENZOBMLP2610001

DYRK kinase substrate

Catalog Number: (ENZOBMLP2610001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide (also known as Woodtide), KKISGRLSPIMTEQ, is derived from transcription factor FKHR with the addition of two lysines to facilitate binding to phosphocellulose membranes. It is a substrate for the DYRK family of kinases.
UOM: 1 * 1 mg
Image Unavailable-ENZOBMLCM1230001

2-Methoxy-antimycin A ≥85%

Supplier: ENZO LIFE SCIENCES
Description: An analog of antimycin A (mixture of antimycin A1, A2, A3 and A4) which binds to the hydrophobic groove of Bcl-2 and Bcl-X<sub>L</sub> thereby inducing apoptosis. It displays selective cytotoxicity for Bcl-X<sub>L</sub>-expressing cells (10 µg/ml). Unlike antimycin A it does not exhibit general mitochondrial toxicity.

Product Image-VERNBL135500AL

BarbLock™ Ultra-Secure Tubing Retainers

Supplier: Saint Gobain Life Sciences
Description: When it comes to retaining flexible tubing and hose onto barbed fittings, BarbLock™ retainers have become the standard in many industries because they solve inherent leak path problems in sensitive and demanding applications. The retainer uses no adhesives or solvents, is ideal for systems transferring delicate liquids or gases.

Product Image-VERN070539-13

PharMed® BPT Tubings

Supplier: Saint Gobain Life Sciences
Description: PharMed® BPT Tubing has been formulated to withstand the rigors of peristaltic pumping action, while providing the biocompatible fluid surface required in sensitive bioprocess applications. With its superior flex life characteristics, PharMed BPT tubing simplifies biopharmaceutical manufacturing processes by reducing production downtime due to pump tubing failure.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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