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Supplier: Biotium
Description: This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Supplier: Biotium
Description: This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Catalog Number: (MFLX96419-24)
Supplier: Avantor Fluid Handling
Description: Long life tubing for any Masterflex® pump used in your pharma and bioprocess applications.
UOM: 1 * 25 Feet

Supplier: Avantor Fluid Handling
Description: Compatible with aggressive chemicals.
Catalog Number: (MFLX06437-24)
Supplier: Avantor Fluid Handling
Description: Longest life of any C-Flex® formulation.
UOM: 1 * 10 Feet

Catalog Number: (MFLX06415-16)
Supplier: Avantor Fluid Handling
Description: Similar to Norprene® but with FDA approval.
UOM: 1 * 500 Feet

Supplier: Avantor Fluid Handling
Description: Long life tubing for any Masterflex® pump used in your pharma and bioprocess applications.
Catalog Number: (MFLX06475-26)
Supplier: Avantor Fluid Handling
Description: Compatible with aggressive chemicals – even MEK!
UOM: 1 * 50 Feet

Catalog Number: (MFLX06475-24)
Supplier: Avantor Fluid Handling
Description: Compatible with aggressive chemicals.
UOM: 1 * 50 Feet

Catalog Number: (MFLX06402-24)
Supplier: Avantor Fluid Handling
Description: Similar to Norprene® but with FDA approval.
UOM: 1 * 50 Feet

Catalog Number: (MFLX06434-26)
Supplier: Avantor Fluid Handling
Description: Ultra performance for ultrapure applications.
UOM: 1 * 25 Feet

Catalog Number: (MFLX95687-26)
Supplier: Avantor Fluid Handling
Description: Protect your light-sensitive samples.
UOM: 1 * 200 Feet

Catalog Number: (620-2721)
Supplier: VWR Collection
Description: Simultaneously displays time of day, temperature, and humidity.
UOM: 1 * 1 items


Supplier: Avantor Fluid Handling
Description: Well-suited for vacuum/pressure applications.
Supplier: Avantor Fluid Handling
Description: Protect your light-sensitive samples.
Catalog Number: (MFLX06508-26)
Supplier: Avantor Fluid Handling
Description: Protect your light-sensitive samples.
UOM: 1 * 25 Feet

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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