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Image Unavailable-BOSSBS-1370R-CY3

Anti-ATM Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1370R-CY3)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1370R-CY7

Anti-ATM Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1370R-CY7)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-1370R-A647

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1370R-A647)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Product Image-DRAE6809180

Accessories for portable single gas detector, X-am® 5100

Supplier: Dräger
Description: Electrochemical sensor (XS), O₂, Range: 0 - 25 %

Product Image-665-0248

inoLab® Multi 9310 IDS Multi-Parameter Meter (pH/Conductivity/DO), Bench

Supplier: WTW
Description: The inoLab® Multi 9310 is ideal for all laboratories that require complete documentation, or want to have the most efficient, error-free measurement processes. For the measurement of a single parameter from pH, conductivity and DO.

Product Image-SCOI285103553

Platinum electrode, ScienceLine

Catalog Number: (SCOI285103553)
Supplier: SI Analytics
Description: Single platinum electrode, with glass shaft and ring shaped sensor (Ø 6 mm). For titration purposes.
UOM: 1 * 1 items
Product Image-DICKR400

Accessories for temperature chart recorders, KT

Catalog Number: (DICKR400)
Supplier: DICKSON
Description: Single K-TC replaceable temperature sensor
UOM: 1 * 1 items
Image Unavailable-BOSSBS-1370R-A750

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1370R-A750)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Product Image-662-9218

pH electrodes for field measurements, Polyplast™

Supplier: HAMILTON BONADUZ
Description: Polyplast electrodes have a shatterproof plastic shaft. They are ideal for portable measurements or as entry level sensors for basic laboratory applications.

Product Image-MFLX31201-65

Masterflex® Single-Use Sanitary Gaskets, TPE, Avantor®

Supplier: Avantor Fluid Handling
Description: Ensure a tight seal in your sanitary fluid line.

Certificates 3A Sanitary approval

Product Image-MFLX72072-30

LeviFlow Single-Use Centrifugal Pump Accessories

Supplier: Avantor Fluid Handling
Description: Optimize performance of your Levitronix Centrifugal Pump.

CE Compliant

Image Unavailable-99311-0.1ML-F

Potassium ionophore I - cocktail A, Selectophore™ ion sensor material, Supelco®

Catalog Number: (99311-0.1ML-F)
Supplier: Merck
Description: Ready-to-use ion selective liquid for the preparation of microelectrodes in micropipettes
UOM: 1 * 0,1 mL
Image Unavailable-D9564-10MG

4',6'-Diamidino-2-phenylindole dilactate (DAPI dilactate) ≥98% (by HPLC) used in nuclear staining, Sigma-Aldrich®

Catalog Number: (D9564-10MG)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: A high sensitivity dye used to detect single nucleic acid molecules. DAPI has been shown to detect a single DNA molecule in solution, and to detect femtograms of DNA in single cells and chloroplasts.
UOM: 1 * 10 mg
Product Image-734-3323

VWR®, Single-Use Transfer Hose with SterilEnz™ Connections

Supplier: VWR Collection
Description: Avantor's high pressure single-use transfer hose with Avantor SterilEnz™ connections maintain the durability of high pressure hose products while providing the benefits and flexibility of single-use assemblies.

Product Image-HACHISEF12103

Ion selective electrodes, Fluoride, IntelliCAL™

Supplier: Hach
Description: IntelliCAL™ ISEF121 is a digital combination fluoride ion selective electrode (ISE) with a non-refillable, single junction reference and built-in temperature sensor. The solid-state sensor design eliminates membrane replacement and allows for dry storage of the ISE.

Product Image-SCOI285103212

pH electrodes, single, ScienceLine

Supplier: SI Analytics
Description: Single electrodes with plug head and Silamid® reference system.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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