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Image Unavailable-BOSSBS-13456R-A350

Anti-GMEB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-13456R-A350)
Supplier: Bioss
Description: GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones. GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, such as testis, bone marrow, placenta and fetal tissues. It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure. GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1. The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling. This acts to increase sensitivity to low concentrations of glucocorticoids. In addition, GMEB-2 functions as an auxiliary factor required for parvovirus replication.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13456R-FITC

Anti-GMEB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-13456R-FITC)
Supplier: Bioss
Description: GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones. GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, such as testis, bone marrow, placenta and fetal tissues. It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure. GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1. The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling. This acts to increase sensitivity to low concentrations of glucocorticoids. In addition, GMEB-2 functions as an auxiliary factor required for parvovirus replication.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-6377R-A750

Anti-Deformed Epidermal Autoregulatory Factor 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-6377R-A750)
Supplier: Bioss
Description: Suppressin, also known as DEAF1 is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localises to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
UOM: 1 * 100 µl
Product Image-E529-500ML

Sodium chloride 5 mol/l (5 N) in aqueous solution for biotechnology, sterile

Catalog Number: (E529-500ML)
Supplier: VWR Chemicals
Description: Common source of salts for media propagation of many organisms.
UOM: 1 * 500 mL

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Product Image-0241-2.5KG

Sodium chloride ≥99.9% for biotechnology

Supplier: VWR Chemicals
Description: Common source of salts for media propagation of many organisms.

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Product Image-33614.265

Sodium chloride ≥99.5%, Gen-Apex Molecular biology grade

Catalog Number: (33614.265)
Supplier: VWR Chemicals
Description: Sodium chloride ≥99.5%, Gen-Apex Molecular biology grade
UOM: 1 * 500 g

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Product Image-3624-05

Sodium chloride ≥99.0% (by argentometric titration), crystals, BAKER ANALYZED® ACS, J.T.Baker®

Supplier: Avantor
Description: Sodium chloride ≥99.0% (by argentometric titration), crystals, BAKER ANALYZED® ACS, J.T.Baker®

MSDS Certificates

Image Unavailable-BOSSBS-13454R-A680

Anti-GMEB1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-13454R-A680)
Supplier: Bioss
Description: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
UOM: 1 * 100 µl
Image Unavailable-0278.9050

Sodium chloride, crystals, BAKER ANALYZED®, J.T.Baker®

Supplier: Avantor
Description: Sodium chloride, crystals, BAKER ANALYZED®, J.T.Baker®

MSDS

Product Image-85812.290

Sodium chloride 0,5 mol/l 0,5 N in aqueous solution, AVS TITRINORM volumetric solution

Catalog Number: (85812.290)
Supplier: VWR Chemicals
Description: Sodium chloride 0,5 mol/l 0,5 N in aqueous solution, AVS TITRINORM volumetric solution
UOM: 1 * 1 L

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Image Unavailable-PRSI10-329

Anti-r-c242Fab-SEA Recombinant Antibody

Catalog Number: (PRSI10-329)
Supplier: ProSci Inc.
Description: Anti-r-c242Fab-SEA Recombinant Antibody
UOM: 1 * 0,1 mg

New Product


Product Image-X190-5KG

Sodium chloride, high purity

Supplier: VWR Chemicals
Description: Sodium chloride, high purity

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Image Unavailable-BOSSBS-13454R-CY7

Anti-GMEB1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-13454R-CY7)
Supplier: Bioss
Description: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
UOM: 1 * 100 µl
Image Unavailable-GERB5462

Sand, crystalline Ø 0.1 - 0.5 mm, washed, calcinated

Supplier: GERBER FUNKE
Description: Crystalline, calcined quality.

Product Image-7713-70

Sodium chloride 99.0-100.5% (dried basis), granular, GenAR® USP for haemodialysis, Macron Fine Chemicals™

Supplier: MACRON AVANTOR BRAND
Description: Sodium chloride 99.0-100.5% (dried basis), granular, GenAR® USP for haemodialysis, Macron Fine Chemicals™

MSDS Certificates

Image Unavailable-87605.30

Sodium chloride ≥99.99% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Sodium chloride ≥99.99% (metals basis)

MSDS Certificates

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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