You Searched For: jnk1

Catalog Number: (ENZOADI900106)

Supplier: ENZO LIFE SCIENCES

Description: For the quantitative determination of [pThr183/Tyr185]Jnk1/2 in cell lysates of human, mouse, and rat origin.

UOM: 1 * 1 KIT

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Catalog Number: (BWRLBS3630)

Supplier: Bioworld Technology

Description: Synthetic peptide, corresponding to amino acids 150-200 of Human JNK1.

UOM: 1 * 100 µG

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Catalog Number: (BWRLBS1544)

Supplier: Bioworld Technology

Description: Synthetic peptide, corresponding to amino acids 150-200 of Human JNK1.

UOM: 1 * 100 µG

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Catalog Number: (BWRLAP0370)

Supplier: Bioworld Technology

Description: Synthetic peptide, corresponding to amino acids 150-200 of Human JNK1.

UOM: 1 * 100 µG

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Catalog Number: (BWRLBS4763)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Threonine 183.

UOM: 1 * 100 µG

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Catalog Number: (BOSSBS-2592R)

Supplier: Bioss

Description: Anti-JNK1 / JNK2 / JNK3 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Catalog Number: (BWRLBS3631)

Supplier: Bioworld Technology

Description: Synthetic peptide, corresponding to amino acids 150-200 of Human JNK1.

UOM: 1 * 100 µG

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Catalog Number: (BWRLBS4764)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Tyrosine 185.

UOM: 1 * 100 µG

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Supplier: ENZO LIFE SCIENCES

Description: Host: Rabbit

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Catalog Number: (ENZOADI905649100)

Supplier: ENZO LIFE SCIENCES

Description: The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also know as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinases belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.

UOM: 1 * 100 µG

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Catalog Number: (BOSSBS-1640R-A750)

Supplier: Bioss

Description: JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BWRLBS4322)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Threonine 183 and Tyrosine 185.

UOM: 1 * 100 µG

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Catalog Number: (BOSSBS-1640R-A680)

Supplier: Bioss

Description: JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BWRLBS6448)

Supplier: Bioworld Technology

Description: Recombinant full length Human JNK1.

UOM: 1 * 100 µG

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Catalog Number: (USBI037211)

Supplier: US Biological

Description: Anti-MAPK8 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

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Catalog Number: (BOSSBS-0501R-A750)

Supplier: Bioss

Description: JNK1(MAPK8) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrome c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7. The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity. The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes.

UOM: 1 * 100 µl

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