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Image Unavailable-BOSSBS-7551R

Anti-TNFAIP3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7551R)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-A647

Anti-TNIP3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-7551R-A647)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-7551R-A680

Anti-TNFAIP3 interacting protein 3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-7551R-A680)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterised human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-A350

Anti-TNIP3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-7551R-A350)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-CY7

Anti-TNIP3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-7551R-CY7)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-A555

Anti-TNIP3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-7551R-A555)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-CY3

Anti-TNIP3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7551R-CY3)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-A750

Anti-TNFAIP3 interacting protein 3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-7551R-A750)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterised human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-FITC

Anti-TNIP3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-7551R-FITC)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9568R

Anti-TNIP1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-9568R)
Supplier: Bioss
Description: Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NFâ…¹B expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-CY5

Anti-TNIP3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-7551R-CY5)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-CY5.5

Anti-TNIP3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7551R-CY5.5)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-A488

Anti-TNIP3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-7551R-A488)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7551R-HRP

Anti-TNIP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-7551R-HRP)
Supplier: Bioss
Description: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl
Image Unavailable-USBI146495

Anti-TNIP3 Rabbit Polyclonal Antibody

Catalog Number: (USBI146495)
Supplier: US Biological
Description: Anti-TNIP3 Rabbit Polyclonal Antibody
UOM: 1 * 100 µG
Product Image-PRSI5303

Anti-TNIP3 Rabbit Polyclonal Antibody

Catalog Number: (PRSI5303)
Supplier: ProSci Inc.
Description: ABIN3 Antibody: The nuclear factor NF-kappa B plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kappa B activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kappa B activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kappa B activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kappa B inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kappa B in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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