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Product Image-PIER22107

Pierce™ PEGylated SMCC Crosslinkers, Heterobifunctional

Supplier: Thermo Fisher Scientific
Description: Cross linkers are used for the identification of near-neighbour protein relationships and ligand-receptor interactions. Homobifunctional, amine-reactive NHS esters or imidates, and heterobifunctional, amine-reactive, photoactivatable phenyl azides are the most commonly used crosslinkers for these applications.

Product Image-PIER62262

Dyes, DyLight™

Supplier: Thermo Fisher Scientific
Description: DyLight™ Dyes have absorption spectra ranging from 350 nm to 770 nm and match the output wavelengths of common fluorescence instrumentation.

Product Image-PIER22298

BMPS (3-Maleimidopropionic acid N-hydroxysuccinimide ester), Pierce™

Catalog Number: (PIER22298)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.9 Å).
UOM: 1 * 50 mg
Image Unavailable-PIERA35393

DSP (Dithiobis(succinimidyl propionate)), No-Weigh™ Format, Pierce™

Catalog Number: (PIERA35393)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.
UOM: 1 * 10 mg
Product Image-PIER22349

SIA (N-Succinimidyl iodoacetate)

Catalog Number: (PIER22349)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce SIA is a very short (1.5 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
UOM: 1 * 50 mg
Product Image-PIER26174

Sulpho-LC-SDA (Sulpho-NHS-LC-Diazirine) (Sulphosuccinimidyl 6-(4,4′-azipentanamido)hexanoate), Pierce™

Catalog Number: (PIER26174)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce Sulfo-LC-SDA (Sulfo-NHS-LC-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 12.5Å spacer arm separates the two photoreactive groups.
UOM: 1 * 50 mg
Product Image-PIER26175

Sulpho-SDAD (Sulpho-NHS-SS-Diazirine) (Sulphosuccinimidyl 2-[(4,4′-azipentanamido)ethyl]-1,3′-dithiopropionate], Pierce™

Catalog Number: (PIER26175)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce Sulfo-SDAD (Sulfo-NHS-SS-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 13.5Å spacer arm containing a cleavable disulfide bond separates the two photoreactive groups.
UOM: 1 * 50 mg
Product Image-PIER22312

Sulpho-MBS (3-Maleimidobenzoyl-N-hydroxysulphosuccinimide ester sodium salt), Pierce™

Catalog Number: (PIER22312)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce Sulfo-MBS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
UOM: 1 * 50 mg
Product Image-AATB371

5(6)-Carboxytetramethylrhodamine succinimidyl ester [5(6)-TAMRA SE] ≥95%

Supplier: AAT BIOQUEST
Description: The succinimidyl esters of 5-TAMRA, 6-TAMRA or the mixed isomers are the primary labeling reagents for the preparation of orange fluorescent bioconjugates, including peptide, protein, nucleotide and nucleic acid conjugates, especially fluorescent antibodies and avidin derivatives used in immunochemistry.

Product Image-PIER22308

EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester), Pierce™

Catalog Number: (PIER22308)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce EMCS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22586

DSP (Dithiobis(succinimidyl propionate)), Pierce™

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.

MSDS

Product Image-PIER21111

Sulpho-KMUS, Pierce™

Catalog Number: (PIER21111)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce Sulfo-KMUS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (16.3 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22311

MBS (N-Succinimidyl 3-maleimidobenzoate), Pierce™

Catalog Number: (PIER22311)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22295

AMAS (N-Succinimidyl maleimidoacetate), Pierce™

Catalog Number: (PIER22295)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce AMAS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a very short spacer arm (4.4 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22329

SIAB (N-Succinimidyl (4-iodoacetyl)aminobenzoate), Pierce™

Catalog Number: (PIER22329)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
UOM: 1 * 50 mg
Product Image-PIER21651

LC-SPDP (Succinimidyl 6-[3-(2-pyridylthio)propionamidohexanoate), Pierce™

Catalog Number: (PIER21651)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce LC-SPDP is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
UOM: 1 * 50 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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