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Image Unavailable-BOSSBS-4286R-FITC

Anti-VAV3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-4286R-FITC)
Supplier: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-A750

Anti-VAV3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-4286R-A750)
Supplier: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organisation and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-A647

Anti-VAV3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-4286R-A647)
Supplier: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Product Image-216-3248

Grating, White

Catalog Number: (216-3248)
Supplier: MULTIROIR
Description: <p><span style="color:black">Durable HDPE grating designed for laboratories. Its open-grid design ensures liquid drainage, minimizing slip risks. Resistant to chemicals and easy to disinfect, it supports strict hygiene standards. Quick to assemble with a clipping system, it’s ideal for safe, clean, and efficient lab environments.</span></p>
UOM: 1 * 1 items

New Product


Product Image-312-0116

Bag closures with scoop/spoon, WeLoc® Scoop

Supplier: WELOC
Description: These sealing clips feature an integrated measuring scoop/spoon. They are convenient for many types of applications in the domestic, medical and industrial field, where both a seal and a measure is required. The clips are made from high quality Polyamide 6.6 material from DuPont® and therefore perfect for use in the demanding pharmaceutical and laboratory environment.

Image Unavailable-BOSSBS-4286R-A555

Anti-VAV3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-4286R-A555)
Supplier: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10118R-FITC

Anti-MST1R Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-10118R-FITC)
Supplier: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10118R-A555

Anti-MST1R Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-10118R-A555)
Supplier: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10118R-A350

Anti-MST1R Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-10118R-A350)
Supplier: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Product Image-111-2583

Vertical fold flat disposable masks, F600 series

Supplier: JSP
Description: Vertical fold flat respirator with foam padded adjustable nose clip and extended chin coverage.

Product Image-OXOIAG0031A

Accessories for Anaerobic Systems, Oxoid

Supplier: THERMO FISHER DIAGNOSTICS
Description: Where an AnaeroGen sachet is placed in a sealed jar, the atmospheric oxygen in the jar is rapidly absorbed with the simultaneous generation of carbon dioxide. This novel method differs from others commonly used in that the reaction proceeds with no evolution of hydrogen, and therefore, does not require a catalyst. Furthermore, water is not required to activate the reaction. When used as directed, the AnaeroGen sachet will reduce the oxygen level in the jar to below 1% within 30 minutes. The resulting carbon dioxide level will be between 9% and 13%.
CampyGen Compact for 1 or 2 Petri dishes, is a simple system for generating microaerobic conditions. The system consists of a plastic pouch and sealing clip and a paper gas generating sachet. The paper sachet contains ascorbic acid which reacts on contact with air to produce the microaerobic conditions for the growth of microaerophilic organisms.

Product Image-JSPAANX060-230-000

Visors and carriers for Evolution® safety helmets, Surefit™

Supplier: JSP
Description: Visor carrier clips into universal slot ear defender housing for the Evolution® safety helmet range. Available with polycarbonate or acetate visors to offer protection against high speed particles, liquid droplets and molten metal.

Image Unavailable-BOSSBS-1037R-CY5.5

Anti-F2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1037R-CY5.5)
Supplier: Bioss
Description: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1037R-A750

Anti-DCP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1037R-A750)
Supplier: Bioss
Description: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
UOM: 1 * 100 µl
Image Unavailable-MMMA7100317692

3M™ Clear Reusable Polycon Earplug Storage Box

Catalog Number: (MMMA7100317692)
Supplier: 3M
Description: Robust reusable storage case to store 3M™ earplugs safely and securely. Case includes belt clip for convenient storage and easy access. Transparent colour allows for quick visual confirmation that the product is in the box.
UOM: 1 * 50 items
Product Image-141-0363

Baskets, mobile injectors, mobile units, covers and injector nozzles for laboratory glassware washing machines

Supplier: MIELE
Description: Accessories for Glassware washing machines, A 834 injector nozzle, screw thread, Height-adjustment clip with additional side holes, Ø×L: 8×150 mm

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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