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Supplier: ENZO LIFE SCIENCES AG
Description: Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.

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Supplier: ENZO LIFE SCIENCES AG
Description: Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.

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Supplier: Cayman Chemical
Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC<sub>50</sub> = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.

Supplier: ENZO LIFE SCIENCES AG
Description: Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.

New Product

Supplier: Saint Gobain Life Sciences
Description: Pure-Fit SIB eliminates entrapment and leak points that can occur with traditional assembly systems. The unique internal design eliminates voids or dead space that can lead to turbulence or stagnation of fluid flow creating the potential for bacterial growth.

Supplier: Saint Gobain Life Sciences
Description: Pure-Fit SIB eliminates entrapment and leak points that can occur with traditional assembly systems. The unique internal design eliminates voids or dead space that can lead to turbulence or stagnation of fluid flow creating the potential for bacterial growth.

Supplier: Apollo Scientific
Description: 2,8-Dichloroquinoline 98%

Supplier: Apollo Scientific
Description: 2,8-Quinolinediol

Supplier: Apollo Scientific
Description: 2,8-Dimethylquinoline hydrochloride

Supplier: Apollo Scientific
Description: 2,8-Dichlorocyclooctanone 95%

Supplier: Apollo Scientific
Description: 4-Chloro-2,8-dimethylquinoline

Catalog Number: (APOSOR911962-1G)
Supplier: Apollo Scientific
Description: 6-Chloro-2,8-dimethylquinoline 95%
UOM: 1 * 1 g


Catalog Number: (APOSOR309320-1G)
Supplier: Apollo Scientific
Description: 7-Bromo-2,8-dimethylquinoline
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: 4,6-Dichloro-2,8-dimethylquinoline

Supplier: Apollo Scientific
Description: 4-Amino-2,8-dimethylquinoline

Catalog Number: (APOSOR309315-1G)
Supplier: Apollo Scientific
Description: 7-Bromo-2,8-dimethyl-4-hydroxyquinoline
UOM: 1 * 1 g


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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