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Product Image-ACRO207340050

Retinoic acid 97%

Supplier: Thermo Fisher Scientific
Description: Retinoic acid 97%

MSDS

Image Unavailable-BOSSBS-3900R-HRP

Anti-CYP2R1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-3900R-HRP)
Supplier: Bioss
Description: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4917R-A488

Anti-BGLAP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-4917R-A488)
Supplier: Bioss
Description: Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2987R-A750

Anti-Vitamin D Receptor/VDR Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-2987R-A750)
Supplier: Bioss
Description: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7759R

Anti-GGCX Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7759R)
Supplier: Bioss
Description: GGCX is a 758 amino acid multi-pass membrane protein. Localized to the membrane of the endoplasmic reticulum, GGCX functions to mediate the vitamin K-dependent carboxylation of glutamate residues on target proteins, thereby producing calcium binding gamma-carboxyglutamate (Gla) residues on these proteins and simultaneously converting vitamin K to vitamin K epoxide. GGCX exists as a monomer and, via its ability to modify glutamate residues, it accomplishes the post-translational changes that are necessary for the activity of all vitamin K-dependent proteins (such as blood coagulation and bone matrix proteins). Defects in the gene encoding GGCX are the cause of combined deficiency of vitamin K-dependent clotting factors 1 (VKCFD1) and PXE-like disorder with multiple coagulation factor deficiency, both of which are characterized by abnormal skin, blood or bone function.
UOM: 1 * 100 µl
Product Image-ACRO241040010

L(-)-Carnitine 99+%

Supplier: Thermo Fisher Scientific
Description: L(-)-Carnitine 99+%

MSDS

Image Unavailable-ABCAAB142766-5

25-Hydroxyvitamin D3 ≥98%

Catalog Number: (ABCAAB142766-5)
Supplier: Abcam
Description: The major circulating metabolite of vitamin D3 (Cholecalciferol). Calcifediol also has mineralisng properties.
UOM: 1 * 5 mg
Image Unavailable-APOSBIN0610-1KG

Nicotinamide 99%

Supplier: Apollo Scientific
Description: Nicotinamide 99%

Product Image-20155.237

L(+)-Ascorbic acid, TECHNICAL

Supplier: VWR Chemicals
Description: L(+)-Ascorbic acid, TECHNICAL

MSDS Certificates

Product Image-ACRO421060010

D-ɑ-Tocopherol acetate 97%

Catalog Number: (ACRO421060010)
Supplier: Thermo Fisher Scientific
Description: Appearance: Clear yellow Viscous liquid
UOM: 1 * 1 g

MSDS Certificates


Image Unavailable-BOSSBS-3900R-A750

Anti-CYP2R1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-3900R-A750)
Supplier: Bioss
Description: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3900R-FITC

Anti-CYP2R1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-3900R-FITC)
Supplier: Bioss
Description: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3900R-A680

Anti-CYP2R1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3900R-A680)
Supplier: Bioss
Description: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
UOM: 1 * 100 µl
Image Unavailable-D1878-5G

2,6-Dichlorophenolindophenol sodium salt hydrate, BioReagent for the determination of vitamin C, Sigma-Aldrich®

Supplier: Merck
Description: 2,6-Dichloroindophenol sodium salt hydrate is a blue redox dye.

Image Unavailable-A19560.30

Thiamine hydrochloride, (max. 5% H₂O) 99% (dry weight)

Supplier: Thermo Fisher Scientific
Description: Thiamine hydrochloride, (max. 5% H₂O) 99% (dry weight)

MSDS Certificates

Image Unavailable-BNCB0872-500

Anti-RBP1 Mouse Monoclonal Antibody (Biotin) [clone: RBP/872]

Supplier: Biotium
Description: Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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