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Image Unavailable-BOSSBS-13281R-CY7

Anti-RASA1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-13281R-CY7)
Supplier: Bioss
Description: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13281R-CY5

Anti-RASA1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-13281R-CY5)
Supplier: Bioss
Description: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
UOM: 1 * 100 µl
Product Image-HELI49464975

PharmaFocus® Premium Reinforced Silicone Tubing

Supplier: Freudenberg Medical Europe GmbH
Description: PharmaFocus® Premium Reinforced Silicone Tubing is available with single-braid reinforcement for enhanced performance in high pressure and vacuum applications. All reinforced silicone tubing is manufactured with an inner layer of platinum-cured silicone for ultra-pure fluid transfer and meets a diverse range of pharmaceutical and bioprocessing applications.

Image Unavailable-ANTIA247217-96

Human Coxsackievirus B IgM ELISA Kit

Catalog Number: (ANTIA247217-96)
Supplier: ANTIBODIES.COM
Description: Human Coxsackievirus B IgM ELISA kit is a trapping Enzyme-Linked Immunosorbent Assay designed for the <i><i>in vitro</i></i> qualitative determination of human Coxsackievirus B IgM in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Image Unavailable-BOSSBS-11427R-A680

Anti-CRSP9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11427R-A680)
Supplier: Bioss
Description: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors. Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation. Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11427R-A647

Anti-MED7 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11427R-A647)
Supplier: Bioss
Description: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
UOM: 1 * 100 µl
Product Image-18-1169-12

Accessories and spare parts for ÄKTApilot

Catalog Number: (18-1169-12)
Supplier: Cytiva
Description: O-ring, 3×1, top air trap
UOM: 1 * 25 items
Image Unavailable-ANTIA247215-96

Human Measles Virus IgM ELISA Kit

Catalog Number: (ANTIA247215-96)
Supplier: ANTIBODIES.COM
Description: Human Measles Virus IgM ELISA kit is a trapping Enzyme-Linked Immunosorbent Assay designed for the <i>in vitro</i> qualitative determination of human Measles Virus IgM in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Image Unavailable-ANTIA247211-96

Human Mycoplasma Pneumoniae IgM ELISA Kit

Catalog Number: (ANTIA247211-96)
Supplier: ANTIBODIES.COM
Description: Human Mycoplasma pneumoniae IgM ELISA kit is a trapping Enzyme-Linked Immunosorbent Assay designed for the <i>in vitro</i> qualitative determination of human Mycoplasma pneumoniae IgM in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Product Image-PRSI55-662

Anti-CUZD1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI55-662)
Supplier: ProSci Inc.
Description: Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
UOM: 1 * 400 µl

New Product


Product Image-216-2327

VWR® 24-Hour Urine Container

Catalog Number: (216-2327)
Supplier: VWR Collection
Description: 24-hour 3 L vacuum urine container with aspiration system for vacuum tubes directly integrated in the screw cap.
UOM: 1 * 30 items
Product Image-SARTFT-3-342-125

Qualitative filter papers, technical, creped

Supplier: Sartorius
Description: These filter papers are used for routine analyses like clarification, determination of substances, but also as discs with a center hole for technical applications. Grades with a wet burst resistance >30 kPa are referred to as wet-strengthened and are therefore
suitable for pressure or vacuum filtration.

Image Unavailable-BOSSBS-11427R-FITC

Anti-MED7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11427R-FITC)
Supplier: Bioss
Description: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
UOM: 1 * 100 µl
Product Image-512-3321

Vacuum filtration units

Supplier: Sartorius
Description: Borosilicate glass, anodised aluminium clamp, silicone lid, autoclavable.

Image Unavailable-PERCN9301178

Inline gas filters

Catalog Number: (PERCN9301178)
Supplier: PerkinElmer
Description: This in-line filter removes moisture, oil, and particulate from gas supplies. It consists of a molecular sieve and indicator in a clear acrylic tube. The drierite changes colour at low relative humidity indicating that packing must be changed.
UOM: 1 * 1 items
Product Image-BOHLD620-08

Multiple distributors with ground joints, BOLA

Catalog Number: (BOHLD620-08)
Supplier: Bohlender
Description: PTFE, white. For bottles or reaction vessels with ground joint. For transferring liquids without contamination. For connection to a liquid source or a pressure or vacuum system.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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