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Catalog Number: (BOSSBS-12355R-A555)
Supplier: Bioss
Description: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12355R-A350)
Supplier: Bioss
Description: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12355R-HRP)
Supplier: Bioss
Description: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
UOM: 1 * 100 µl


Catalog Number: (MILFTISNAP2MINI)
Supplier: Merck
Description: Developed to meet the needs of our Western blotting customers, the SNAP i.d. 2.0 system produces blots of a very high quality. Unique vacuum-driven technology and a built-in flow distributor actively drive reagents through the membrane.
UOM: 1 * 1 items


Supplier: LABCONCO
Description: These systems use vacuum along with heat and vortex motion to help speed evaporation and provide an alternative to traditional centrifugal evaporation methods. The systems may be used with a broad range of aggressive chemicals. Heat is supplied by a dry block heating system that, unlike water baths, adds no potential source of contamination and requires no maintenance.

Supplier: Merck
Description: <p>Western blot packages with unbelievable savings! Save time and money by choosing the package that best serves your needs! The SNAP i.d.<sup>®</sup> system applies a vacuum to actively drive reagents through the membrane, promoting antigen binding and thorough washing, enabling you to better optimise your Western blotting.</p>

Supplier: Lenz Laborglas GmbH & CO.KG
Description: DURAN®, borosilicate glass

Catalog Number: (HEWL5065-9908)
Supplier: Agilent
Description: Organic Standard, Caffeine standards kit for LC/MS-Trap OQ/PV, includes 5 ampoules, 5 ml each: 0,1, 0,5, 1,0, 5,0, 10,0, μg/ml caffeine in water, 5 × 5 ml
UOM: 1 * 1 items


Catalog Number: (521-3914)
Supplier: BECKMAN COULTER
Description: Major applications: Pelleting of subcellular fractions in 5 to 30 minutes, plasmid DNA separations in 3 hours.
UOM: 1 * 1 items


Supplier: Freudenberg Medical Europe GmbH
Description: PharmaFocus® Premium Reinforced Silicone Tubing is available with single-braid reinforcement for enhanced performance in high pressure and vacuum applications. All reinforced silicone tubing is manufactured with an inner layer of platinum-cured silicone for ultra-pure fluid transfer and meets a diverse range of pharmaceutical and bioprocessing applications.

Catalog Number: (ANTIA247198-96)
Supplier: ANTIBODIES.COM
Description: Human Toxoplasma IgM ELISA kit is a trapping Enzyme-Linked Immunosorbent Assay designed for the <i>in vitro</i> qualitative determination of human Toxoplasma IgM in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Catalog Number: (ANTIA302965-96)
Supplier: ANTIBODIES.COM
Description: Human Cytomegalovirus IgM ELISA kit is a trapping Enzyme-Linked Immunosorbent Assay designed for the <i><i>in vitro</i></i> qualitative determination of human Cytomegalovirus IgM in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Supplier: Merck
Description: All the individual steps associated with solid phase extraction can be carried out using the LiChrolut® extraction unit. This transparent and vacuum-suitable unit, made of glass, can be used to prepare up to 12 samples simultaneously.
Catalog Number: (BOSSBS-4284R-A750)
Supplier: Bioss
Description: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
UOM: 1 * 100 µl


Catalog Number: (521-3759)
Supplier: BECKMAN COULTER
Description: Major applications: Pelleting of subcellular fractions; proteins; RNA.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-4284R-A350)
Supplier: Bioss
Description: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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