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Apicidin ≥99% (by HPLC, TLC)

Catalog Number: (ENZOBMLGR3400005)
Supplier: ENZO LIFE SCIENCES
Description: HDAC inhibitor
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLAK5110001

FLUOR DE LYS® HDAC1 fluorometric drug discovery assay kit

Catalog Number: (ENZOBMLAK5110001)
Supplier: ENZO LIFE SCIENCES
Description: The HDAC1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC1 included in the kit.
UOM: 1 * 1 KIT
Product Image-ENZOBMLAK5320001

HDAC/SIRT chemiluminescent drug discovery kit, CHEMILUM DE LYS®

Catalog Number: (ENZOBMLAK5320001)
Supplier: ENZO LIFE SCIENCES
Description: The HDAC/SIRT chemiluminescent drug discovery kit is a complete assay system designed to measure histone deacetylase (HDAC) and sirtuin activity in cell or nuclear extracts, immunoprecipitates or purified enzymes.
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLAK5030001

FLUOR DE LYS® HDAC fluorometric cellular activity assay kit

Catalog Number: (ENZOBMLAK5030001)
Supplier: ENZO LIFE SCIENCES
Description: The HDAC fluorometric cellular activity assay allows the determination of deacetylase activity within an undisturbed cellular environment and provides accurate activity information that is reflective of endogenous regulation. It also allows the study of the effects of upstream regulators on deacetylase activity and the detection of inhibitors or activators that act indirectly to affect deacetylase activity.
UOM: 1 * 1 KIT
Image Unavailable-ICNA0215206425

Sodium-2-propylvalerate, crystalline powder

Supplier: MP Biomedicals
Description: Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3α and GSK-3β. Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400 μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells.

Image Unavailable-ENZOBMLAK5120001

FLUOR DE LYS®-Green HDAC2 fluorometric drug discovery assay kit

Catalog Number: (ENZOBMLAK5120001)
Supplier: ENZO LIFE SCIENCES
Description: The HDAC2 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC2 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or kinetic assay of the enzyme under varying conditions.
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLAK5180001

FLUOR DE LYS® HDAC8 fluorometric drug discovery kit

Catalog Number: (ENZOBMLAK5180001)
Supplier: ENZO LIFE SCIENCES
Description: A Fluor-de-Lys® fluorescent assay system. The HDAC8 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC8 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions. The Fluor de Lys® HDAC8 assay is based on the Fluor de Lys® Substrate and Fluor de Lys® Developer combination. The assay procedure has two steps. First, the Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with HDAC6. Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the Fluor de Lys®Developer produces a fluorophore.
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLAK5310001

FLUOR DE LYS® HDAC3/NCOR1 fluorometric drug discovery kit

Catalog Number: (ENZOBMLAK5310001)
Supplier: ENZO LIFE SCIENCES
Description: The HDAC3/NCOR1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC3 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions.
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLAK5160001

FLUOR DE LYS® HDAC6 fluorometric drug discovery kit

Catalog Number: (ENZOBMLAK5160001)
Supplier: ENZO LIFE SCIENCES
Description: A Fluor-de-Lys® fluorescent assay system. The HDAC6 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC6 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions. The Fluor de Lys® HDAC6 assay is based on the Fluor de Lys® Substrate and Fluor de Lys® Developer combination. The assay procedure has two steps. First, the Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with HDAC6. Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the Fluor de Lys®Developer produces a fluorophore.
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLAK5000001

FLUOR DE LYS® HDAC fluorometric activity assay kit

Catalog Number: (ENZOBMLAK5000001)
Supplier: ENZO LIFE SCIENCES
Description: The FLUOR DE LYS® HDAC fluorometric activity assay kit is a sensitive and convenient alternative to protocols utilizing radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. It is based on the unique FLUOR DE LYS® (Fluorimetric Histone deAcetylaseLysyl) substrate and developer combination and provides an assay that can be carried out in two simple mixing steps, all on the same 96-well plate. Histone deacetylase inhibitors have shown promise as anti-tumor agents and naturally this has stimulated interest in the screening of compounds for HDAC inhibition.
UOM: 1 * 1 KIT
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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