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Strychnine 98%

Supplier: Thermo Scientific
Description: Strychnine 98%

MSDS

Product Image-PRSI55-210

Anti-GNAT3 Rabbit Polyclonal Antibody

Catalog Number: (PRSI55-210)
Supplier: ProSci Inc.
Description: Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody. Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium. GNAT3 can functionally couple to taste receptors to transmit intracellular signal: receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors. Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide-1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP. Thus, may modulate the gut capacity to absorb sugars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.
UOM: 1 * 400 µl

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STRYCHNINE NITRATE 1 * 10 mg

Catalog Number: (PROOLGCFOR0658.00)
Supplier: LGC Standards PROMOCHEM
Description: STRYCHNINE NITRATE 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-PROOMM0658.02

STRYCHNINE N-OXIDE HYDROCHLORIDE 1 * 100 mg

Catalog Number: (PROOMM0658.02)
Supplier: LGC Standards PROMOCHEM
Description: STRYCHNINE N-OXIDE HYDROCHLORIDE 1 * 100 mg
UOM: 1 * 100 mg
Image Unavailable-ABCAAB120416-100

STRYCHNINE HYDROCHLORIDE 1 * 100 mg

Catalog Number: (ABCAAB120416-100)
Supplier: Abcam
Description: STRYCHNINE HYDROCHLORIDE 1 * 100 mg
UOM: 1 * 100 mg

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STRYCHNINE NITRATE 1 * 500 mg

Catalog Number: (PROOMM0658.00)
Supplier: LGC Standards PROMOCHEM
Description: STRYCHNINE NITRATE 1 * 500 mg
UOM: 1 * 500 mg
Image Unavailable-55513-100MG

Organic reference standard, Spermine, analytical standard, Supelco®

Catalog Number: (55513-100MG)
Supplier: Merck
Description: Organic Standard, Spermine, ≥99,0% (GC), 97,0 - 103,0% (T)
UOM: 1 * 100 mg
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Hypotaurine, white prills

Supplier: MP Biomedicals
Description: Hypotaurine is a Non-specific, endogenous inhibitory glycine receptor agonist.

Product Image-ANTIA83535-100

Anti-alpha 1 Glycine Receptor Goat Polyclonal Antibody

Catalog Number: (ANTIA83535-100)
Supplier: ANTIBODIES.COM
Description: Goat polyclonal antibody to alpha 1 Glycine Receptor for ELISA, WB and IHC with samples derived from human, mouse and rat.
UOM: 1 * 100 µG

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Spermine-(N,N'-bis(3-aminopropyl)-1,4-butanediamine) ≥97%, colorless solid

Supplier: MP Biomedicals
Description: Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

Image Unavailable-ICNA0210047401

Spermine tetrahydrochloride ≥96%, white powder

Supplier: MP Biomedicals
Description: Spermine is a naturally occuring polyamine that occurs in all eukaryotes, but is rare in prokaryotes. It is essential for cell growth in both normal and neoplastic tissue.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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