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Image Unavailable-BOSSBS-0622R-FITC

Anti-SNCG Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0622R-FITC)
Supplier: Bioss
Description: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0622R-A488

Anti-SNCG Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-0622R-A488)
Supplier: Bioss
Description: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1428R-A350

Anti-Claudin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-1428R-A350)
Supplier: Bioss
Description: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7856R-CY5.5

Anti-ALOXE3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7856R-CY5.5)
Supplier: Bioss
Description: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12239R-CY3

Anti-ZNF750 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-12239R-CY3)
Supplier: Bioss
Description: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 750 is a 723 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZNF750 contains one conserved C2H2 zinc finger domain and is expressed in the skin, lungs, prostate, placenta and thymus. ZNF750 is also expressed in primary human keratinocytes but not in fibroblasts. Mutations in the gene encoding ZNF750 cause Seborrhea-like dermatitis with psoriasiform, a condition characterized by a chronic and diffuse rash on the face and hyperkeratosis of skin over the elbows, soles, knees and palms.
UOM: 1 * 100 µl
Image Unavailable-OXOITS0001A

Transport swabs

Supplier: THERMO FISHER DIAGNOSTICS
Description: Effective transportation of throat, vaginal, wound and skin swabs conforming to highest medical device classification - Class II a surgically invasive transient use. All swabs have soft rayon tips, which are inert and non-toxic to micro-organisms.
The addition of charcoal in the medium is considered to neutralise bacterial toxins and other inhibitory substances and has been shown to increase the recovery of Neisseria gonorrhoeae.

Image Unavailable-BOSSBS-12239R-A647

Anti-ZNF750 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-12239R-A647)
Supplier: Bioss
Description: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 750 is a 723 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZNF750 contains one conserved C2H2 zinc finger domain and is expressed in the skin, lungs, prostate, placenta and thymus. ZNF750 is also expressed in primary human keratinocytes but not in fibroblasts. Mutations in the gene encoding ZNF750 cause Seborrhea-like dermatitis with psoriasiform, a condition characterized by a chronic and diffuse rash on the face and hyperkeratosis of skin over the elbows, soles, knees and palms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12239R-A488

Anti-ZNF750 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12239R-A488)
Supplier: Bioss
Description: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 750 is a 723 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZNF750 contains one conserved C2H2 zinc finger domain and is expressed in the skin, lungs, prostate, placenta and thymus. ZNF750 is also expressed in primary human keratinocytes but not in fibroblasts. Mutations in the gene encoding ZNF750 cause Seborrhea-like dermatitis with psoriasiform, a condition characterized by a chronic and diffuse rash on the face and hyperkeratosis of skin over the elbows, soles, knees and palms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12239R-HRP

Anti-ZNF750 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-12239R-HRP)
Supplier: Bioss
Description: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 750 is a 723 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZNF750 contains one conserved C2H2 zinc finger domain and is expressed in the skin, lungs, prostate, placenta and thymus. ZNF750 is also expressed in primary human keratinocytes but not in fibroblasts. Mutations in the gene encoding ZNF750 cause Seborrhea-like dermatitis with psoriasiform, a condition characterized by a chronic and diffuse rash on the face and hyperkeratosis of skin over the elbows, soles, knees and palms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11308R

Anti-SRD5A1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11308R)
Supplier: Bioss
Description: Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone, which mediates androgen effects on target tissues. The enzyme exists as two isoforms: type 1, which is expressed mainly in the skin; and type 2, which is expressed mainly in the prostate. In cultured human skin cells, 5a-Reductase 1 shows heterogeneity of protein, and has different levels of transcriptional and translational expression. 5a-Reductase 1 is expressed in all portions of the hair follicle, whereas 5a-Reductase 2 is expressed only in mesenchymal portions. In addition, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma. The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12239R-A680

Anti-ZNF750 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-12239R-A680)
Supplier: Bioss
Description: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 750 is a 723 amino acid member of the Kr_ppel C2H2-type zinc finger protein family. localised to the nucleus, ZNF750 contains one conserved C2H2 zinc finger domain and is expressed in the skin, lungs, prostate, placenta and thymus. ZNF750 is also expressed in primary human keratinocytes but not in fibroblasts. Mutations in the gene encoding ZNF750 cause Seborrhea-like dermatitis with psoriasiform, a condition characterised by a chronic and diffuse rash on the face and hyperkeratosis of skin over the elbows, soles, knees and palms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12239R-FITC

Anti-ZNF750 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-12239R-FITC)
Supplier: Bioss
Description: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 750 is a 723 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZNF750 contains one conserved C2H2 zinc finger domain and is expressed in the skin, lungs, prostate, placenta and thymus. ZNF750 is also expressed in primary human keratinocytes but not in fibroblasts. Mutations in the gene encoding ZNF750 cause Seborrhea-like dermatitis with psoriasiform, a condition characterized by a chronic and diffuse rash on the face and hyperkeratosis of skin over the elbows, soles, knees and palms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6575R-HRP

Anti-S100 A7A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6575R-HRP)
Supplier: Bioss
Description: Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
UOM: 1 * 100 µl
Product Image-112-4322

Nitrile gloves, Microflex® 93-823

Supplier: Ansell
Description: These disposable nitrile gloves provide chemical and liquid protection. The most advanced glove in type I and IV allergy prevention, the Microflex 93-823 has been clinically proven to decrease redness and itchiness associated with contact dermatitis. Engineered without the use of chemical additives (including accelerators) that are known skin irritants, the 93-823 is safe for those with sensitive skin or prone to allergic reactions.

Image Unavailable-BOSSBS-7815R-CY5

Anti-NEK8 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-7815R-CY5)
Supplier: Bioss
Description: Required for renal tubular integrity.Tissue specificity: Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7815R-CY5.5

Anti-NEK8 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7815R-CY5.5)
Supplier: Bioss
Description: Required for renal tubular integrity.Tissue specificity: Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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