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Image Unavailable-BOSSBS-7645R-A488

Anti-DNAJA3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-7645R-A488)
Supplier: Bioss
Description: TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localized splice variants of human Tid1 designated hTid1S and hTid1L. These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70. They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity. Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha. A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis. Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected. It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities. Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7645R-A750

Anti-HCA57 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-7645R-A750)
Supplier: Bioss
Description: TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localised splice variants of human Tid1 designated hTid1S and hTid1L. These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70. They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity. Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha. A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis. Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected. It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities. Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.
UOM: 1 * 100 µl

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Product Image-129-1039

Disposal bin, SHARPSGUARD®, yellow

Supplier: DANIELS HEALTHCARE LIMITED
Description: SHARPSGUARD® yellow is a similar range of containers to SHARPSGUARD® orange, with the added advantage that they can also be used to dispose of sharps contaminated with medicinal products and their residues other than cytotoxic and/or cytostatic medicines. To ensure the containers are safe and simple to use the opaque doors clearly show when the door is in the temporary or fully closed position. The SHARPSGUARD® yellow range is designed to be incinerated or disposed of by other authorised process.

Product Image-129-0726

Disposal bin, SHARPSGUARD®, orange

Supplier: DANIELS HEALTHCARE LIMITED
Description: PP.

Image Unavailable-GOSSCOX800A-02

Gosselin™ Waste and Sharp Containers

Catalog Number: (GOSSCOX800A-02)
Supplier: Corning
Description: Waste containers made of Polypropylene (PP), NFX 30-511 compliant.
UOM: 1 * 65 items

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Product Image-JUSU05930WH

Biohazard Waste Containers

Supplier: JUSTRITE MANUFACTURING
Description: These leakproof sturdy steel containers with foot-operated and self-closing lid may be used to store contaminated laundry as well as other regulated waste (not for sharps). They have a biohazard bag which is held securely around the circumference of the can top.

Product Image-PRSI27-925

Anti-TOX Rabbit Polyclonal Antibody

Catalog Number: (PRSI27-925)
Supplier: ProSci Inc.
Description: Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1; MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1; MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.
UOM: 1 * 50 µG
Product Image-DANIDD210

Waste container, SHARPSGUARD® eco pharmi

Supplier: DANIELS HEALTHCARE LIMITED
Description: SHARPSGUARD® eco pharmi are ideal general-purpose waste containers for the disposal of pharmaceutical waste in original packaging, such as unused pills, no sharps.

Image Unavailable-SARS86.1203

Biohazard Bags

Supplier: SARSTEDT
Description: These disposal bags are ideal for the containment and disposal of contaminated laboratory and hospital consumables. A 50 µm thick polypropylene bag with a durable wide base seam ensures a good resistance to tear and puncturing. However, in view of the inherent risk of injury, sharp or pointed objects must never be placed into the bags.

Image Unavailable-PERSAGBL-7027-0000

AccuForge Gem® Scientific Blade Dispenser

Catalog Number: (PERSAGBL-7027-0000)
Supplier: PERSONNA MEDICAL
Description: AccuForge Pop-Up Dispenser provides quick, easy blade access for high volume applications. Each disposable dispenser contains 100 blades constructed of .009" carbon with aluminum back steel and 3-facet edges for sharpness.
UOM: 1 * 100 items

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Product Image-BELAF389520000

Ampoule breaker, box style, Break-Safe™, SP Bel-Art

Catalog Number: (BELAF389520000)
Supplier: Bel-Art Products, a Part of SP
Description: The box style design of the ampoule opener allows one handed opening of up to 3 ampoules at a time by simply pressing down on lid. Ampoule necks are snapped clean and are contained within the device while fingers stay away from sharp edges. After removing ampoule contents, turning the device upside down over a trash receptacle can safely discard ampoules and tops. Made from transparent copolyester plastic.
UOM: 1 * 1 items
Product Image-MFLX06407-21

Masterflex® Transfer Tubing, Tygon® E-3603, Non-DEHP, Avantor®

Supplier: Avantor Fluid Handling
Description: Pliable formulation for sharp radius bending.

Product Image-233-1454

Microscopy scissors

Supplier: RSG
Description: Stainless steel.

Product Image-69278-3

PCR Molecular Size Marker

Catalog Number: (69278-3)
Supplier: Merck Millipore (Novagen)
Description: PCR Molecular Size Marker contains a mixture of eight defined DNA fragments ranging from 50 to 2000 bp at convenient size intervals for characterising small DNA products. The markers are supplied in gel loading buffer containing two tracking dyes that do not interfere with UV illumination of ethidium bromide-stained bands. A separate vial of 6X Loading Buffer is included. Each vial of markers is sufficient for 50 lanes on TBE or TAE agarose stained with ethidium bromide. The recommended amount for loading (5 µl) produces bands of even intensity that are bright, sharp and easy to photograph.
UOM: 1 * 1 items
Image Unavailable-EVBIEB07168

Anti-SPEN / SHARP Goat Polyclonal Antibody

Catalog Number: (EVBIEB07168)
Supplier: Everest Biotech
Description: Anti-SPEN / SHARP Goat Polyclonal Antibody
UOM: 1 * 0,1 mg
Image Unavailable-USBIS1010-89A

Anti-SHARP Goat Polyclonal Antibody

Catalog Number: (USBIS1010-89A)
Supplier: US Biological
Description: Anti-SHARP Goat Polyclonal Antibody
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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